Aim To report anatomical and functional outcomes after surgical repair of acute-onset vs delayed-onset rhegmatogenous retinal detachments (RDs) following acute posterior vitreous detachment (PVD). Methods A retrospective, comparative interventional cohort study where patients presenting to a single-centre retina practice between October 2015 and March 2020 with delayed RDs (diagnosed ≥42 days after initial presentation of acute PVD) were compared with a 2:1 age-matched and gender-matched acute RD cohort (PVD and RD at initial presentation). The primary outcome was the final attachment rate and single surgery anatomic success (SSAS) at 3 months after RD repair. Results A total of 210 eyes were analysed—70 in the delayed RD group and 140 in the acute RD group. SSAS was 58/70 (82.9%) for the delayed RD group and 112/140 (80%) for the acute RD group (p=0.71). At the time of RD diagnosis, mean (SD) logarithm of minimum angle of resolution visual acuity (VA) was 0.51 (0.70) (Snellen, 20/65) in the delayed RD group vs 1.04 (0.92) (Snellen, 20/219) in the acute RD group (p<0.001). Mean VA was better at 1 and 3 months post-repair in the delayed RD group (p=0.005 and 0.041, respectively) but similar by 6 months, 12 months and at the final visit post-repair (p=0.48, 0.27, and 0.23, respectively). Conclusions Delayed-onset RDs occurring ≥6 weeks after initial presentation to a retina specialist with an acute PVD generally had better VA at the time of RD diagnosis and faster post-surgical visual recovery compared with acute-onset RDs diagnosed at the initial presentation. No significant difference in anatomic outcomes was seen between the two groups. Data are available upon reasonable request.

中文翻译：

---

急性玻璃体后脱离后早发性孔源性视网膜脱离与迟发性孔源性视网膜脱离修复后的结果

目的 报告急性后玻璃体脱离 (PVD) 后急性发作与迟发性孔源性视网膜脱离 (RD) 手术修复后的解剖和功能结果。方法 一项回顾性比较介入队列研究，将 2015 年 10 月至 2020 年 3 月期间接受单中心视网膜治疗的延迟性 RD（在首次出现急性 PVD ​​后≥42 天诊断）的患者与 2:1 年龄匹配的患者进行比较。性别匹配的急性 RD 队列（初次就诊时的 PVD ​​和 RD）。主要结果是 RD 修复后 3 个月的最终附着率和单次手术解剖成功率 (SSAS)。结果 总共分析了 210 只眼睛，其中延迟 RD 组 70 只，急性 RD 组 140 只。延迟 RD 组的 SSAS 为 58/70 (82.9%)，急性 RD 组的 SSAS 为 112/140 (80%) (p=0.71)。在 RD 诊断时，延迟 RD 组的最小分辨率视力 (VA) 的平均 (SD) 对数为 0.51 (0.70) (Snellen, 20/65)，而延迟 RD 组为 1.04 (0.92) (Snellen, 20/219) ）在急性 RD 组中（p<0.001）。延迟 RD 组修复后 1 个月和 3 个月的平均 VA 更好（分别为 p=0.005 和 0.041），但在修复后 6 个月、12 个月和最后一次就诊时相似（p=0.48、0.27 和分别为 0.23）。结论 与初次就诊时诊断出的急性发作 RD 相比，首次就诊后 ≥6 周出现急性 PVD ​​的迟发性 RD 在 RD 诊断时通常具有更好的 VA，并且术后视力恢复更快。两组之间的解剖结果没有显着差异。数据可根据合理要求提供。