The use of cannabis for medical symptoms is increasing despite limited evidence for its efficacy. Expectancies-prior beliefs about a substance or medicine-can modulate use patterns and effects of medicines on target symptoms. To our knowledge, cannabis expectancies have not been studied for their predictive value for symptom relief. The 21-item Cannabis Effects Expectancy Questionnaire-Medical (CEEQ-M) is the first longitudinally validated measure of expectancies for cannabis used for medical symptoms. The questionnaire was developed for a randomized clinical trial of the effect of state cannabis registration (SCR) card ownership on symptoms of pain, insomnia, anxiety, and depression in adults (N = 269 across six questionnaire administrations). Item-level analyses (n = 188) demonstrated between-person stability of expectancies and no aggregate, within-person expectancy changes 3 months after individuals gained access to SCR cards. Exploratory factor analysis (n = 269) indicated a two-factor structure. Confirmatory factor analysis at a later timepoint (n = 193) demonstrated good fit and scalar invariance of the measurement model. Cross-lagged panel models across 3 and 12 months (n = 187 and 161, respectively) indicated that CEEQ-M-measured expectancies did not predict changes in self-reported cannabis use; symptoms of pain, insomnia, anxiety, and depression; and well-being. However, greater baseline cannabis use predicted more positive expectancy changes. The findings suggest that the CEEQ-M is psychometrically sound. Future work should clarify at what timescales cannabis expectancies have predictive value and how cannabis expectancies for medical symptoms are maintained and diverge from other substance use expectancies. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

中文翻译：

---

大麻效应预期问卷-医学（CEEQ-M）：临床试验中的初步心理测量特性和纵向验证。

尽管大麻功效的证据有限，但使用大麻来治疗医学症状的情况仍在增加。期望——对某种物质或药物的先验信念——可以调节药物的使用模式和对目标症状的影响。据我们所知，尚未研究大麻预期对症状缓解的预测价值。包含 21 项的大麻影响预期问卷 - 医疗 (CEEQ-M) 是第一个纵向验证的大麻用于医疗症状的预期衡量标准。该调查问卷是为一项随机临床试验而开发的，该试验旨在研究国家大麻登记 (SCR) 卡所有权对成人疼痛、失眠、焦虑和抑郁症状的影响（六次调查问卷管理中 N = 269）。项目级分析 (n = 188) 证明了人与人之间的预期稳定性，并且在个人获得 SCR 卡后 3 个月内，人与人之间的总体预期没有变化。探索性因素分析（n = 269）表明存在双因素结构。稍后时间点（n = 193）的验证性因素分析证明了测量模型的良好拟合和标量不变性。3 个月和 12 个月的交叉滞后面板模型（n = 187 和 161，分别）表明，CEEQ-M 测量的预期并不能预测自我报告的大麻使用的变化；疼痛、失眠、焦虑和抑郁症状；和幸福。然而，更多的基线大麻使用预示着更积极的预期变化。研究结果表明，CEEQ-M 在心理测量上是合理的。未来的工作应阐明大麻预期在什么时间范围内具有预测价值，以及大麻对医疗症状的预期如何维持并与其他物质使用预期有所不同。（PsycInfo 数据库记录 (c) 2023 APA，保留所有权利）。