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An intrinsically stretchable multi-biochemical sensor for sweat analysis using photo-patternable ecoflex
npj Flexible Electronics ( IF 14.6 ) Pub Date : 2023-07-24 , DOI: 10.1038/s41528-023-00268-x
Seungwan Kim , Joohyuk Kang , Injun Lee , Jinhyeong Jang , Chan Beum Park , Wonryung Lee , Byeong-Soo Bae

Ecoflex is widely used in bioelectronics due to its outstanding properties of low modulus and large stretchability. For its use as an encapsulation layer in multi-channel wearable devices, a patterning procedure is essential. However, conventional patterning strategies for Ecoflex, such as soft lithography, punching, and laser ablation, lack sufficient quality and process compatibility. To address this, we propose a process-compatible method of patterning Ecoflex by developing Photo-patternable Ecoflex (PPE). The PPE layer, used as an encapsulation layer, effectively dissipates strain energy at homogeneous interfaces, resulting in a 50% increase in electrical conductance under 250% strain. Using PPE, we fabricated intrinsically stretchable multi-sensors that monitor bio-signals like glucose, lactate, pH, and humidity in sweat. These sensors maintain durable sensitivity under strain up to 50% and for 1000 cycles at 20% strain. Finally, we mounted these stretchable multi-chemical sensors on an arm to monitor glucose and lactate levels in sweat.



中文翻译:

一种本质上可拉伸的多生化传感器,用于使用可照片图案化的 ecoflex 进行汗液分析

Ecoflex因其低模量和大拉伸性能的突出特性而广泛应用于生物电子领域。为了将其用作多通道可穿戴设备中的封装层,图案化过程是必不可少的。然而,Ecoflex 的传统图案化策略,例如软光刻、冲压和激光烧蚀,缺乏足够的质量和工艺兼容性。为了解决这个问题,我们提出了一种通过开发可光图案化 Ecoflex (PPE) 来图案化 Ecoflex 的工艺兼容方法。PPE层用作封装层,可有效耗散均匀界面处的应变能,从而在250%应变下电导率增加50%。使用 PPE,我们制造了本质上可拉伸的多传感器,用于监测汗液中的葡萄糖、乳酸、pH 值和湿度等生物信号。这些传感器在高达 50% 的应变下和在 20% 应变下可保持 1000 个周期的持久灵敏度。最后,我们将这些可拉伸的多化学传感器安装在手臂上,以监测汗液中的葡萄糖和乳酸水平。

更新日期:2023-07-25
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