An in vitro dynamic bioreactor model for evaluating antimicrobial effectiveness on periodontal polymicrobial biofilms: a proof-of-concept study,Journal of Periodontology

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An in vitro dynamic bioreactor model for evaluating antimicrobial effectiveness on periodontal polymicrobial biofilms: a proof-of-concept study
Journal of Periodontology ( IF 4.3 ) Pub Date : 2023-09-19 , DOI: 10.1002/jper.23-0086
Srinivas Sulugodu Ramachandra _{1,

2} , Fekade Bruck Sime ₃ , Saiyuri Naicker ₃ , Pingping Han _{1,

4} , Ryan Sb Lee _{1,

4} , Steven C Wallis ₃ , Jason A Roberts _{3,

5,

6} , Sašo Ivanovski _{1,

4}

Affiliation

The aim of this study was to investigate an in vitro dynamic bioreactor model by evaluating the antimicrobial effect of clinically relevant amoxicillin doses on polymicrobial microcosm biofilms derived from subgingival plaque.

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