RNA turnover regulates the quality and quantity of cellular gene expression through a coordinated cavalcade of enzymes, factors, and phase transitions. In this issue, Brothers et al reveal the importance of balanced communication between the Xrn1 exonuclease and the EDC4 decapping factor to coordinate P-body dynamics and maintain cellular fitness.

中文翻译：

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P 体和 XRN1-EDC4 轴的动态“能力”能力

RNA 周转通过一系列酶、因子和相变的协调来调节细胞基因表达的质量和数量。在本期中，Brothers等人揭示了 Xrn1 核酸外切酶和 EDC4 脱帽因子之间平衡通讯对于协调 P-body 动力学和维持细胞健康的重要性。