Electromyography (EMG) signal is the electrical potential generated by contracting muscle cells. Long-term and accurate EMG monitoring is desirable for neuromuscular function assessment in clinical and the human–computer interfaces. Herein, we report a skin-integrated, biocompatible, and stretchable silicon microneedle electrode (SSME) inspired by the plant thorns. The silicon microneedles are half encapsulated by the polyimide (PI) to enhance the adaptability to deformation and resistance to fatigue. Thorn-like SSME is realized by the semi-additive method with a stretchability of not less than 36%. The biocompatibility of SSME has been verified using cytotoxicity tests. EMG monitoring in motion and long-term has been conducted to demonstrate the feasibility and performance of the SSME, which is compared with a commercial wet electrode. Hopefully, the strategies reported here can lead to accurate and long-term EMG monitoring, facilitating an effective and reliable human–computer interface.

肌电图 (EMG) 信号是肌肉细胞收缩时产生的电位。长期准确的肌电图监测对于临床和人机界面中的神经肌肉功能评估是可取的。在此，我们报告了一种受植物刺启发的皮肤集成、生物相容性和可拉伸的硅微针电极（SSME）。硅微针被聚酰亚胺（PI）半封装，增强变形适应能力和抗疲劳能力。刺状SSME采用半加成法实现，拉伸率不低于36%。SSME 的生物相容性已通过细胞毒性测试得到验证。已经进行了运动和长期肌电图监测，以证明 SSME 的可行性和性能，并与商用湿电极进行比较。希望这里报告的策略能够实现准确和长期的肌电图监测，促进有效和可靠的人机界面。