Wearable sweat sensors are becoming increasingly popular for their robust capabilities in non-invasive, dynamic, and continuous real-time monitoring of biological information. Real-time monitoring of large-scale samples is crucial for realizing intelligent health. A major bottleneck for enabling large-scale sweat elucidation is the fabrication of wearable sensors equipped with microfluidic devices and flexible electrodes in a cost-effective, homogeneous performance and rapid large-scale way. Herein, a “Screen+Wax”-printing technique was introduced to prepare these components and construct “Lego Bricks” type wearable sweat sensor sensor to monitor sweat Na⁺ and K⁺. Flexible electrode arrays and paper-based microfluidic layers (they act as building blocks) were fabricated on polyethylene terephthalate and paper surfaces, respectively, using screen printing and wax printing. Gold nanoparticles and Na⁺/K⁺ ion-selective membranes were modified on the electrode surfaces by electrodeposition and drop coating, respectively. In this work, we highlight the excellent performance of the “Lego Bricks” type wearable sweat sensor in testing the Na⁺ and K⁺ imbalance of sweat from different body regions during exercise and, more significantly, to track the physical activity during prolonged exercise under different interventions. Furthermore, the prepared “Lego Bricks” wearable sweat ion electrochemical sensor is demonstrated to be capable of large-scale samples elucidation with outstanding performance and cost-effectiveness, which is expected to deeply integrate sweat monitoring into physical activity, providing an important tool for intelligent health.

可穿戴汗液传感器因其在非侵入性、动态和连续实时生物信息监测方面的强大功能而变得越来越受欢迎。大样本的实时监测对于实现智慧健康至关重要。实现大规模汗液澄清的一个主要瓶颈是以经济高效、性能均匀且快速大规模的方式制造配备微流体装置和柔性电极的可穿戴传感器。在此，引入“丝网+蜡”印刷技术来制备这些组件并构建“乐高积木”型可穿戴汗液传感器来监测汗液Na ⁺和K ⁺。柔性电极阵列和纸基微流体层（它们充当构建块）分别使用丝网印刷和蜡印刷在聚对苯二甲酸乙二醇酯和纸表面上制造。分别通过电沉积和滴涂法在电极表面修饰金纳米粒子和Na ⁺ /K ⁺离子选择性膜。在这项工作中，我们重点介绍了“乐高积木”型可穿戴汗液传感器在测试运动过程中身体不同部位汗液的Na ⁺和K ⁺不平衡方面的出色表现，更重要的是，在长时间运动时跟踪身体活动不同的干预措施。此外，所制备的“乐高积木”可穿戴汗离子电化学传感器被证明能够进行大规模样本解析，具有出色的性能和成本效益，有望将汗液监测深度融入身体活动中，为智能运动提供重要工具。健康。