This paper examines time-series vaccine effectiveness on COVID-19 infection with/without a bivalent booster dose by 6 age groups such as 18–29, 30–49, 50–64, 65–79, 80+, and all_ages respectively. CDC’s COVID data on rates of COVID-19 cases and deaths by updated (bivalent) booster status was used in this study. This result concludes that there is no difference between vaccines with or without a bivalent booster dose for preventing COVID-19 infection in 6 age groups 18–29, 30–49, 50–64, 65–79, 80+, and all_ages. Vaccination is effective in two age groups of 65-79 and 80+ for preventing COVID-19 infection. However, vaccine effectiveness against COVID-19 infection has not been confirmed in the 18–29 and 30–49 age groups.

中文翻译：

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疫苗对 COVID-19 感染的影响，按年龄组进行二价加强

本文研究了 6 个年龄组（分别为 18-29 岁、30-49 岁、50-64 岁、65-79 岁、80 岁以上和所有年龄组）在使用/不使用二价加强剂量的情况下对 COVID-19 感染的时间序列疫苗有效性。本研究使用了 CDC 关于按更新（二价）加强状态划分的 COVID-19 病例率和死亡率的 COVID 数据。该结果得出的结论是，在 18-29、30-49、50-64、65-79、80+ 和所有年龄段 6 个年龄组中，使用或不使用二价加强剂量的疫苗预防 COVID-19 感染没有差异。疫苗接种对于 65-79 岁和 80 岁以上两个年龄组可有效预防 COVID-19 感染。然而，疫苗针对 COVID-19 感染的有效性尚未在 18-29 岁和 30-49 岁年龄组中得到证实。