Circadian dysfunction is a core feature of bipolar disorder and may be due, at least in part, to abnormalities of non-visual photoreception. We critically review the evidence for light hypersensitivity in bipolar disorder and discuss how this may shape future research and clinical innovation, with a focus on a possible novel mechanism of action for lithium.

中文翻译：

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双相情感障碍对光的敏感性：对研究和临床实践的影响

昼夜节律功能障碍是双相情感障碍的核心特征，可能至少部分归因于非视觉感光异常。我们批判性地回顾了双相情感障碍中光过敏的证据，并讨论了这将如何影响未来的研究和临床创新，重点是锂可能的新作用机制。