Anti-inflammatory therapy involving IL-1β inhibition might reduce the risk of cardiovascular events in individuals with clonal haematopoiesis by increasing the number of fibroblast-like cells in the fibrous cap region of atherosclerotic plaques, thereby stabilizing the plaque and reducing the likelihood of rupture.

中文翻译：

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成纤维细胞样细胞响应抗 IL-1β 治疗促进斑块稳定性

涉及 IL-1β 抑制的抗炎治疗可能会增加动脉粥样硬化斑块纤维帽区域中成纤维细胞样细胞的数量，从而稳定斑块并降低破裂的可能性，从而降低克隆性造血个体发生心血管事件的风险。