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The role of the molecular autopsy in sudden cardiac death in young individuals
Nature Reviews Cardiology ( IF 49.6 ) Pub Date : 2024-01-23 , DOI: 10.1038/s41569-024-00989-0
Julia C. Isbister , Christopher Semsarian

A molecular autopsy is undertaken in cases of sudden cardiac death with no definitive cause found after conventional autopsy, with the aim of identifying a pathological genetic variant that could account for the death. Greater awareness of malignant arrhythmias in the absence of structural changes in inherited cardiomyopathies has increased the applicability of molecular autopsies, and resulted in improved care of families but new challenges for clinicians.

中文翻译:

分子尸检在年轻人心源性猝死中的作用

对传统尸检后未发现明确原因的心源性猝死病例进行分子尸检,目的是确定可能导致死亡的病理遗传变异。在遗传性心肌病没有结构变化的情况下,人们对恶性心律失常的认识提高,增加了分子尸检的适用性,改善了家庭护理,但也给临床医生带来了新的挑战。
更新日期:2024-01-24
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