Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial,The Lancet Child & Adolescent Health

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Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial
The Lancet Child & Adolescent Health ( IF 36.4 ) Pub Date : 2024-01-22 , DOI: 10.1016/s2352-4642(23)00316-4
Saul N Faust , Richard Haynes , Christine E Jones , Natalie Staplin , Elizabeth Whittaker , Thomas Jaki , Ed Juszczak , Enti Spata , Mandy Wan , Alasdair Bamford , Paul Dimitri , Adam Finn , John Furness , Athimalaipet V Ramanan , Christopher Gale , Katrina Cathie , Simon Drysdale , Jolanta Bernatoniene , Clare Murray , Charles C Roehr , Paul Fleming , Andrew Riordan , Srini Bandi , Deepthi Jyothish , Jennifer Evans , Marieke Emonts , Dominic Kelly , Nazima Pathan , Patrick Davies , Rosie Hague , Louisa Pollock , Malcolm G Semple , Leon Peto , J Kenneth Baillie , Maya Buch , Katie Jeffery , Marian Knight , Wei Shen Lim , Alan Montgomery , Aparna Mukherjee , Andrew Mumford , Kathryn Rowan , Guy Thwaites , Marion Mafham , Jonathan Emberson , Martin J Landray , Peter W Horby , Lucy Chappell , Jeremy Day , DV Dung , Jeremy Day , NN Quang , Prof Binh , E Burhan , B Alisjahbana , J Koirala , S Basnet , E Kestelyn , B Basnyat , P Gyanwali , RL Hamers , P Sandercock , J Darbyshire , D DeMets , R Fowler , D Lalloo , M Munavvar , I Roberts , A Warris , J Wittes , A Craddock-Bamford , J Barton , A Basoglu , R Brown , W Brudlo , E Denis , L Fletcher , S Howard , S Musini , K Taylor , G Cui , B Goodenough , A King , M Lay , D Murray , W Stevens , K Wallendszus , R Welsh , C Crichton , J Davies , R Goldacre , C Harper , F Knight , M Nunn , H Salih , J Welch , M Campbell , G Pessoa-Amorim , M Zayed , J Wiles , G Bagley , S Cameron , S Chamberlain , B Farrell , H Freeman , A Kennedy , A Whitehouse , S Wilkinson , C Wood , C Reith , K Davies , H Halls , L Holland , R Truell , K Wilson , Emma Lingwood , L Howie , M Lunn , Penelope Rodgers , J Amuasi , K Baird , T Bao , B Basnyat , M Bittaye , J Bonney , U D'Alessandro , M Dhimal , P Gyanwali , RL Hamers , T Huyen , A Jagne , A Karkey , E Kestelyn , O Maiga , E Matey , B Nadjm , J Nel , S Pant , K Puspatriani , M Rahardjani , S Raijal , H Rees , A Rimainar , C Roberts , A Rocca , S Shrestha , E Usuf , C Vidaillic , F Wulandari , A Alexander , M Amezaga , C Armah , A Asghar , P Aubrey , K Barker-Williams , A Barnard , J Bartholomew , D Beaumont-Jewell , S Beddows , J Beety , C Birch , P Boyle , M Brend , M Brookes , C Callens , D Campbell , H Campbell , H Cate , E Chambers , K Chapman , A Coe , J Collins , S Crawshaw , S Das , A De Soyza , E Denton , P Dicks , M Dolman , K Donaldson , L Dowden , S Dowling , C Drake , H Duckles-Leech , H Duffy , L Gerdes , K Gibbons , L Gill , K Gilmour , J Goodwin , J Graham , C Green , C Hall , A Hall , K Hampshire , J Hanson , T Harman , H Harper , S Harrison , J Hicks , H Hodgson , M Hough , S Jackson , G Johnson , J Kirk , N Lemoine , C Levett , S Lock , T Lockett , M Logan , K Lomme , J Luo , N McMillan , H Membrey , N Mguni , J Minton , H Monaghan , S Murphy , N Muzengi , M Naz , I Nickson , M Odam , U Ohia , E Okell , A Oliver , K Pearson , K Pine , R Pleass , D Porter , L Porter , A Potter , V Poustie , S Pratt , A Price , A Priest , A Rodgers , C Rook , P Ryan , S Sam , P Sharratt , J Sheffield , J Shenton , K Shirley , T Skinner , H Slade , M Sutu , J Taylor , E Thomas , H Tinkler , A Unsworth , R Usher , W van't Hoff , S Walker , J Walters , E Walton , J Warmington , E Wayman , P Williams , J Williamson , D Williamson , F Yelnoorkar , M Knight , K Hodson , S Pavord , C Williamson , L Bowman , F Chen , R Clarke , M Goonasekara , W Herrington , P Judge , S Ng , D Preiss , C Reith , E Sammons , D Zhu , C Arkley , P Bowker , J Bruce , V Byrne-Watts , G Chapman , G Coleman , T Denwood , J Gray , D Harrison , N Mather , H Pinches , A Rees , S Rees , G Turner , O Abani , A Abbas , F Abbas , J Abbas , K Abbas , M Abbas , S Abbasi , H Abbass , A Abbott , N Abdallah , A Abdelaziz , M Abdelfattah , B Abdelqader , A Abdul , B Abdul , S Abdul , A Abdul Rasheed , A Abdulakeem , R Abdul-Kadir , A Abdullah , A Abdulmumeen , R Abdul-Raheem , N Abdulshukkoor , K Abdusamad , Y Abed El Khaleq , M Abedalla , A Abeer Ul Amna , L Abel , K Abernethy , M Abeywickrema , C 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Ahmed , L Ahmed , M Ahmad , N Ahmed , O Ahmed , R Ahmed , S Ahmad , S H Ahmed , R Ahmed Ali , B Ahmed Mohamud , S Ahmer , A Ahonia , C Aiken , D Ail , M Ainsworth , M Aissa , L Aitken , B Ajay , A Ajibode , A Ajmi , N Akhtar , S Akili , B Akinbiyi , O Akindolie , Y Akinfenwa , O Akinkugbe , I Akinpelu , M Akram , O Aktinade , U Akudi , A Al Aaraj , A Al Balushi , M Al Dakhola , A Al Swaifi , E Al-Abadi , A Alabi , N Aladangady , M Alafifi , A Alam , S Alam , A Al-Asadi , K Alatzoglou , P Albert , L Albon , A Alcala , G Alcorn , S Alcorn , A Aldana , D Alderdice , A Aldesouki , R Aldouri , J Aldridge , N Aldridge , A Alegria , C Alexander , J Alexander , P Alexander , J Al-Fori , L Alghazawi , O Alhabsha , B Al-Hakim , R Alhameed , M Al-Hayali , S Al-Hity , A Ali , F Ali , J Ali , M Ali , N Ali , O Ali , R Ali , S Ali , E Aliberti , J Alin , A Alina , A Alipustain , F Aliyuda , K Alizaedeh , M Al-Jibury , S Al-Juboori , M Al-Khalil , A Alkhudhayri , M Alkhusheh , F Allan , N Allan , A 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Attia , E Attubato , M Attwood , Z Auer , A Aujayeb , A Aung , H Aung , K Aung , N Aung , Y Aung , Z Aung , E Austin , K Austin , A Auwal , M Avari , M Avery , N Aveyard , J Avis , G Aviss , C Avram , P Avram , A Awadelkareem , G Awadzi , M Awaly , A Awan , A Awoseyila , A Aya , E Ayaz , A Ayers , J Azam , A Azeem , M Azharuddin , A Aziz , G Aziz , I Aziz , N Aziz , A Azkoul , A Azman Shah , G Azzopardi , H Azzoug , F Babatunde , M Babi , B Babiker , G Babington , M Babirecki , M Babores , A Babs-Osibodu , S Bacciarelli , R Bachar , M Bachour , G Bacon , J Bacon , B Badal , M Bader , G Badhan , S Badhrinarayanan , J Bae , A Baggaley , A Baggott , D Bagmane , L Bagshaw , K Bahadori , A Bailey , J Bailey , K Bailey , L Bailey , M Bailey , P Bailey , S Bailey , H Baillie , J Baillie , J Bain , V Bains , D Baird , E Baird , S Baird , T Baird , T Baird , Y Baird , A Bajandouh , D Baker , E Baker , J Baker , J Baker , K Baker , M Baker , R Baker , T Baker , V Baker , H Bakere , N Bakerly , M 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Crepet , J Cresswell , M Cribb , D Crilly , L Crisp , N Crisp , D Crocombe , M Croft , J Crooks , H Crosby , E Cross , T Cross , A Crothers , S Crotty , S Crouch , M Crow , A Crowder , K Crowley , T Crowley , R Croysdill , C Cruickshank , I Cruickshank , J Cruise , C Cruz , T Cruz Cervera , D Cryans , H Cui , L Cullen , G Cummings-Fosong , V Cunliffe , N Cunningham , J Cupitt , H Curgenven , G Curnow , D Curran , S Curran , C Currie , J Currie , S Currie , J Curtis , K Curtis , M Curtis , O Curtis , T Curtis , R Cuthbertson , J Cuthill , S Cutler , S Cutts , M Czekaj , P Czylok , E d Sausmarez , S D'Souza , J da Rocha , M Dafalla , A Dagens , H Daggett , J Daglish , S Dahiya , A Dale , K Dale , M Dale , S Dale , J Dales , H Dalgleish , H Dallow , C D'aloia , D Dalton , M Dalton , Z Daly , M Damani , E Damm , A Danga , J Dangerfield , A Daniel , P Daniel , A Daniels , A Dann , S Danso-Bamfo , S Darby , A Darbyshire , P Dargan , P Dark , K Darlington , S Darnell , T Darton , G Darylile , 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Farquhar , H Farr , A Farrell , F Farrukh , J Farthing , S Farzana , R Fasina , A Faterni , M Faterni , S Fathima , N Fatimah , M Faulkner , C Favager , J Fawke , S Fawohunre , A Fazal , A Fazleen , S Fearby , C Fearnley , A Feben , F Fedel , D Fedorova , C Fegan , M Felongo , L Felton , T Felton , K Fenlon , A Fenn , R Fennelly , I Fenner , C Fenton , M Fenton , G Ferenando , C Ferguson , J Ferguson , K Ferguson , S Ferguson , V Ferguson , C Fernado , C Fernandez , D Fernandes , E Fernandez , M Fernandez , S Fernandez Lopez , J Fernandez Roman , J Fernando , A Feroz , P Ferranti , T Ferrari , E Ferrelly , A Ferrera , E Ferriman , S Ferron , N Fethers , B Field , J Field , R Field , K Fielder , L Fieldhouse , A Fielding , J Fielding , S Fielding , A Fikree , S Filipa , S Filson , S Finan , S Finbow , D Finch , J Finch , L Finch , S Finch , N Fineman , L Finlayson , J Finlayson , J Finn , D Finnerty , C Finney , D Finucane , S Fiouni , J Fiquet , P Firi , J Fisher , N Fisher , D Fishman 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Gatenby , E Gaughan , A Gaurav , M Gavrila , J Gaylard , S Gayle , C Geddie , I Gedge , S Gee , F Geele , K Geerthan , M Gellamucho , K Gelly , L Gelmon , S Gelves-Zapata , G Genato , D Gent , N Gent , N Geoghegan , A George , B George , S George , T George , V George , S Georges , D Georgiou , P Gerard , L Germain , H Gerrish , A Getachew , L Gethin , S Gettings , H Ghanayem , B Ghavami Kia , S Ghazal , A Gherman , A Ghosh , D Ghosh , J Ghosh , S Ghosh , S Giannopoulou , M Gibani , C Gibb , B Gibbison , A Gibson , B Gibson , J Gibson , K Gibson , S Gibson , M Gigi , C Gilbert , J Gilbert , K Gilbert , B Giles , J Gilham , M Gill , P Gillen , A Gillesen , K Gillespie , E Gillham , A Gillian , D Gilliland , R Gillott , D Gilmour , L Gilmour , L Ginn , T Giokanini-Royal , A Gipson , B Giri , J Girling , R Gisby , A Gkioni , A Gkoritsa , E Gkrania-Klotsas , A Gladwell , J Glanville , S Glasgow , J Glasgow , J Glass , L Glass , S Glaysher , L Gledhill , E Glenday , A Glennon , J Glossop , J Glover , K Glover , M Glover , J Glover Bengtsson , D Glowski , S Glynn , C Gnanalingam , J Goddard , W Goddard , E Godden , J Godden , S Godlee , E Godson , G Godwin , S Gogoi , A Goh , M Gohel , R Goiriz , S Gokaraju P Harman , A Goldsmith , P Goldsmith , D Gomersall , L Gomez , R Gomez-Marcos , A Gondal , C Gonzalez , J Goodall , V Goodall , A Goodfellow , L Goodfellow , J Goodlife , E Goodwin , C Goodwin , P Goodyear , R Gooentilleke , S Gooseman , S Gopal , C Gordon , S Gordon , R Gore , H Gorick , C Gorman , S Gormely , M Gorniok , D Gorog , M Gorst , T Gorsuch , J Gosai , R Gosling , S Gosling , G Gosney , V Goss , D Gotham , N Gott , E Goudie , N Gould , S Gould , C Goumalatsou , L Gourbault , A Govind , R Govindan , S Gowans , G Gowda , R Gowda , H Gower , P Goyal , S Goyal , C Graham , J Graham , L Graham , R Graham , S Graham , M Graham-Brown , J Grahamslaw , G Grana , T Grandison , L Grandjean , A Grant , D Grant , K Grant , M Grant , P Grant , R Gravell , J Graves , A Gray , C Gray , G Gray , K Gray , N Gray , R Gray , S Gray , A Grayson , F Greaves , P Greaves , A Green , C Green , D Green , F Green , J Green , M Green , N Green , S Green , D Greene , P Greenfield , A Greenhalgh , D Greenwood , S Greer , J Gregory , K Gregory , T Gregory , J Greig , R Grenfell , T Grenier , J Gresty , S Grevatt , G Grey , S Gribben , A Gribbin , A Gribble , N Grieg , D Grieve , B Griffin , D Griffin , M Griffin , S Griffith , A Griffiths , D Griffiths , I Griffiths , M Griffiths , N Griffiths , O Griffiths , S Griffiths , Y Griffiths , S Grigoriadou , S Grigsby , P Grist , E Grobovaite , D Grogono , C Grondin , R Groome , P Grose , L Grosu , J Grounds , M Grout , H Grover , J Groves , N Grubb , J Grundy , F Guarino , S Gudur , J Guerin , S Guettari , S Gulati , V Gulia , H Gunasekara , P Gunasekera , M Gunawardena , K Gunganah , J Gunn , E Gunter , A Gupt , V Gupt , A Gupta , R Gupta , T Gupta , A Gupta-Wright , V Guratsky , A Gureviciute , S Gurram , B Gurung , L Gurung , S Gurung , S Gurung Rai , H Guth , N Guthrine , T H Dinh , R Habibi , B Hack , J Hackett , P Hackney , C Hacon , A Haddad , D Hadfield , N Hadfield , S Hadfield , M Hadjiandreou , N Hadjisavvas , A Haestier , N Hafiz , R Hafiz-Ur-Rehman , J Hafsa , S Hagan , J Hague , N Haider , K Haigh , V Haile , J Hailstone , C Haines , S Hainey , M Hair , B Hairsine , J Hajnik , D Hake , L Hakeem , A Haldeos , W Halder , E Hale , J Hale , C Halevy , P Halford , W Halford , A Halim , A Hall , E Hall , F Hall , H Hall , J Hall , K Hall , L Hall , J Hallas , K Hallas , C Hallett , J Halliday , A Hallman , M Hamdollah-Zadeh , I Hamed-Adekale , B Hameed , M Hameed , I Hamid , M Hamie , R Hamill , B Hamilton , F Hamilton , G Hamilton , L Hamilton , M Hamilton , N Hamilton , S Hamilton , R Hamlin , E Hamlyn , B Hammans , S Hammersley , K Hammerton , B Hammond , E Hammond , L Hammond , S Hammond , F Hammonds , I Hamoodi , J Hampson , L Hampson , L Hamzah , J Han , O Hanci , S Hand , J Handford , S Handrean , N Handzewniak , S Haney , S Hanif , E Hanison , J Hannah , A Hannington , M Hannun , A Hanrath , H Hanratty , D Hansen , A Hanson , H Hanson , K Hanson , S Hanson , A Haqiqi , M Haque , H Harcourt , L Harden , Z Harding , S Hardman , M Hardwick , G Hardy , J Hardy , K Haresh , R Harford , B Hargadon , J Hargraves , C Hargreaves , A Harin , M Haris , E Harlock , M Harmer , M Haroon , J Harper , P Harper , R Harper , S Harrhy , K Harrington , S Harrington , Y Harrington-Davies , J Harris , L Harris , M Harris , N Harris , S Harris , L Harrison , M Harrison , O Harrison , R Harrison , T Harrison , W Harrison , E Harrod , C Hart , D Hart , P Hartidge , L Hartley , J Hartley , R Hartley , T Hartley , W Hartrey , S Hartshorn , A Harvey , M Harvey , H Harwood , Z Harzeli , B Haselden , M Hashimm , T Hashimoto , I Hashmi , J Haslam , Z Haslam , G Hasnip , A Hassan , Z Hassan , S Hassasing , P Hassell , J Hassell , A Hastings , B Hastings , J Hastings , S Hathaway-Lees , J Hatton , J Hau , M Havinden-Williams , S Havlik , D Hawcutt , K Hawes , L Hawes , N Hawes , L Hawker , A Hawkins , J Hawkins , N Hawkins , W Hawkins , D Hawley , E Hawley-Jones , E Haworth , C Hay , A Hayat , J Hayat , M Hayathu , A Hayes , C Hayes , F Hayes , J Hayes , K Hayes , M Hayes , P Hayle , C Haylett , A Hayman , M Hayman , M Haynes , R Hayre , S Haysom , J Hayward , P Haywood , T Hazelton , P Hazenberg , Z He , E Headon , C Heal , B Healy , J Healy , A Hearn , D Heasman , A Heath , D Heath , R Heath , D Heaton , A Heavens , K Hebbron , G Hector , S Heddon , A Hedges , K Hedges , C Heeley , E Heeney , R Heinink , R Heire , I Helgesen , J Hemingway , B Hemmings , S Hemphill , D Hemsley , A Henderson , E Henderson , J Henderson , S Henderson , J Henry , K Henry , L Henry , M Henry , N Henry , D Henshall , G Herdman , R Herdman-Grant , M Herkes , F Hernandez , E Heron , L Heron , E Heselden , P Heslop , T Heslop , S Hester , E Hetherington , J Hetherington , C Hettiarachchi , P Hettiarachchi , H Hewer , J Hewertson , A Hewetson , S Hewins , N Hewitson , C Hewitt , D Hewitt , R Hewitt , S Hey , R Heyderman , M Heydtmann , J Heys , J Heywood , M Hibbert , J Hickey , P Hickey , N Hickey , A Hicks , S Hicks , D Higbee , L Higgins , A Higham , M Highcock , J Highgate , M Hikmat , A Hill , H Hill , J Hill , L Hill , P Hill , U Hill , A Hilldrith , C Hillman-Cooper , J Hilton , Z Hilton , S Hinch , A Hindle , E Hindley , A Hindmarsh , P Hine , K Hinshaw , C Hird , C Hirst , L Hirst , J Hives , H Hlaing , B Ho , R Ho , M Hoare , G Hobden , M Hobrok , S Hobson , C Hodge , S Hodge , L Hodgen , G Hodgetts , H Hodgkinson , S Hodgkinson , D Hodgson , L Hodgson , S Hodgson , G Hodkinson , M Hodson , A Hogan , M Hogben , L Hogg , L Hoggett , A Holborow , C Holbrook , R Holbrook , C Holden , J Holden , M Holden , S Holden , T Holder , N Holdhof , H Holdsworth , M Holland , N Holland , P Holland , S Holland , M Hollands , E Holliday , K Holliday , M Holliday , N Holling , L Hollos , N Hollos , L Holloway , S Holloway , M Hollowday , M Hollyer , A Holman , A Holmes , M Holmes , R Holmes , K Holroyd , B Holroyd-Hind , L Holt , S Holt , A Holyome , M Home , R Homewood , K Hong , L Hoole , C Hooper , S Hope , B Hopkins , S Horler , A Hormis , D Hornan , N Hornby , T Horne , Z Horne , R Horner , C Horrobin , L Horsford , M Horsford , V Horsham , A Horsley , E Horsley , S Horton , J Hosea , T Hoskins , M Hossain , R Hossain , S Hough , C Houghton , K Houghton , R Houlihan , K Housely , H Houston , R Hovvels , L How , J Howard , K Howard , L Howard , M Howard , S Howard , R Howard-Griffin , L Howard-Sandy , S Howe , A Howell , M Howells , K Howlett , S Howlett , R Howman , J Hrycaiczuk , H Htet , N Htoon , S Htwe , Y Hu , C Huah , S Huang , K Hubbard , A Huckle , S Huda , A Hudak , L Hudig , O Hudson , H Hudson , S Hudson , A Hufton , C Huggins , A Hughes , C Hughes , E Hughes , G Hughes , H Hughes , L Hughes , M Hughes , R Hughes , S Hughes , V Hughes , W Hughes , L Huhn , C Hui , R Hulbert , D Hull , G Hull , R Hull , A Hulme , P Hulme , W Hulse , G Hulston , R Hum , M Hume , C Humphrey , A Humphries , J Humphries , C Hunt , F Hunt , J Hunt , K Hunt , L Hunt , M Hunt , S Hunt , A Hunter , C Hunter , E Hunter , K Hunter , N Hunter , R Hunter , S Hunter , F Huq , E Hurditch , J Hurdman , C Hurley , K Hurley , M Husain , S Husaini , C Huson , A Hussain , C Hussain , I Hussain , M Hussain , R Hussain , S Hussain , Y Hussain , M Hussam El-Din , S Hussein , Z Hussein , R Hussey , A Hussien , A Hutchinson , C Hutchinson , D Hutchinson , E Hutchinson , J Hutchinson , C Hutsby , P Hutton , H Huynh , D Hydes , J Hyde-Wyatt , N Hynes , M Hyslop , S I Tay , A Iakovou , K Ibison , M Ibraheim , A Ibrahim , J Ibrahim , M Ibrahim , W Ibrahim , B Icke , A Idowu , M Idrees , N Idrees , H Iftikhar , M Iftikhar , C Igwe , O Igwe , M Ijaz , A Ikomi , C Iles , S Iliodromiti , M Ilsley , L Ilves , F Ilyas , L Imam-Gutierrez , M Iman , C Imray , H Imtiaz , J Ingham , R Ingham , T Ingle , J Inglis , S Inglis-Hawkes , A Ingram , L Ingram , T Ingram , N Innes , P Inns , V Inpadhas , K Inweregbu , A Ionescu , I Iordanov , A Ipe , J Iqbal , M Iqbal , F Iqbal Sait , I Irabor , J Ireland , J Irisari , R Irons , M Irshad , J Irvine , V Irvine , R Irving , M Ishak , E Isherwood , G Isitt , A Islam , M Islam , S Islam , A Islim , A Ismail , O Ismail , C Ison , M Israa , S Isralls , M Ivan , C Ivenso , N Ivin , A Ivy , S Iwanikiw , K Ixer , M Iyer , K Jabbar , C Jack , J Jackman , S Jackman , A Jackson , B Jackson , E Jackson , H Jackson , L Jackson , M Jackson , N Jackson , Y Jackson , J Jacob , P Jacob , R Jacob , N Jacques , A Jafar , D Jafferji , A Jaffery , C Jagadish , V Jagannathan , M Jagpal , N Jai , S Jain , S Jaiswal , D Jajbhay , B Jallow , Y Jaly , R Jama , A Jamal , S Jamal , Z Jamal , Y Jameel , A James , C James , K James , L James , M James , N James , O James , P James , R James , S James , T James , J Jameson , L Jamieson , A Jamison , P Jane , K Janes , A Janmohamed , D Japp , P Jaques , V Jardim , C Jardine , C Jarman , E Jarnell , E Jarvie , C Jarvis , R Jarvis , P Jastrzebska , H Javed , A Javier , M Jawad , L Jawaheer , A Jayachandran , D Jayachandran , A Jayadev , A Jayakumar , D Jayaram , R Jayaram , G Jayasekera , T Jayatilleke , A Jayebalan , J Jeater , S Jeddi , V Jeebun , M Jeelani , H Jeffery , K Jeffery , R Jeffrey , N Jeffreys , B Jeffs , C Jeffs , J Jeganathan Ponraj , D Jegede , T Jemima , I Jenkin , S Jenkin , A Jenkins , C Jenkins , D Jenkins , E Jenkins , I Jenkins , P Jenkins , S Jenkins , F Jennings , J Jennings , L Jennings , V Jennings , E Jerome , D Jerry , G Jervis , E Jessup-Dunton , J Jesus Silva , C Jetha , K Jethwa , S Jhanji , K Jian , Z Jiao , L Jimenez , A Jimenez Gil , J Jith , T Joefield , S Johal , N Johal , K Johannessen , A Johari , A John , M John , N John , E Johns , M Johns , A Johnson , E Johnson , K Johnson , L Johnson , M Johnson , N Johnson , O Johnson , R Johnson , B Johnston , C Johnston , J Johnston , S Johnston , V Johnston , D Johnstone , E Johnstone , J Johnstone , M Joishy , S Jone , A Jones , B Jones , C Jones , D Jones , E Jones , G Jones , J Jones , K Jones , L Jones , M Jones , N Jones , N Jones , O Jones , P Jones , R Jones , R E Jones , S Jones , T Jones , R Jonnalagadda , R Jordache , M Jordan , S Jordan , A Jose , L Jose , S Jose , A Joseph , G Joseph , P Joseph , R Joseph , S Joseph , D Joshi , P Joshi , T Joshi , M Joshi , B Josiah , L Joy , T Joyce , H Ju , A Ju Wen Kwek , A Judd , E Jude , J Juhl , S Jujjavarapu , M Juniper , K Kabiru Dawa , M Kacar , N Kadam , N Kader , A Kailey , M Kain , G Kakoullis , R Kalayi , A KalBhushan , R Kaliannan Periyasami , E Kallistrou , T Kalmus Eliasz , S Kalsoom , E Kam , J Kamara , A Kamath , P Kamath , R Kamath , S Kamerkar , N Kametas , M Kamfose , C Kamundi , D Kanabar , L Kane , O Kankam , T Kannan , A Kant , V Kapil , R Kapoor , S Kapoor , S Kaprapina , S Kar , J Kara , E Karbasi , S Karelia , R Kark , S Karmali , V Karunanithi , N Karunaratne , N Kasianczuk , A Kasiappan Balasubramanian , V Kasipandian , R Kassam , J Kathirgamachelvam , V Katsande , K Kaul , D Kaur , J Kaur , S Kaur , Z Kausar , L Kavanagh , S Kavanagh , M Kawser , A Kay , J Kay , R Kay , S Kay , J Kayappurathu , C Kaye , A Kazeem , M Ke , T Keady , R Kearns , N Kearsley , J Keating , L Keating , E Keddie-Gray , B Keegan , R Keen , N Keenan , J Kefas , S Kegg , L Keith , U Keke , J Kellett , J Kelliher , A Kelly , E Kelly , H Kelly , L Kelly , M Kelly , R Kelly , S Kelly , M Kelly-Baxter , O Kelsall , M Keltos , T Kemp , E Kendall , A Kendall-Smith , S Kennard , J Kennedy , M Kennedy , S Kennedy-Hay , J Kenny , M Kent , L Keogan , A Keough , D Kernaghan , A Kerr , C Kerrison , A Kerry , H Kerslake , I Kerslake , H Kerss , J Keshet-Price , G Keyte , A Khadar , A Khalid , H Khalid , M Khalid , S Khalid , T Khalifa , A Khalil , A Khalil , S Khalil , A Khan , B Khan , F Khan , K Khan , M Khan , N Khan , O Khan , R Khan , S Khan , T Khan , W Khan , Z Khan , M Khan Tharin , U Khatana , J Khatri , H Khatun , T Khatun , M Kheia , J Khera , H Khin , N Khoja , K Khokhar , J Khoo , C Khurana , J Kibaru , F Kibutu , A Kidd , M Kidd , J Kidney , S Kidney , W Kieffer , J Kilbane , C Kilby , E Killen , B Kilner , S Kilroy , B Kim , J Kim , M Kim , A Kimber , S Kimber , B King , H King , J King , K King , M King , R King , S King , V King , E King-Oakley , L Kingsmore , D Kinnear , F Kinney , S Kiran , A Kirby , A Kirk , J Kirk , A Kirkby , E Kirkham , G Kirkman , L Kirkpatrick , U Kirwan , T Kitching , L Kitto , L Kittridge , S Klaczek , F Kleemann , S Kmachia , C Knapp , L Knibbs , A Knight , S Knight , T Knight , E Knights , J Knights , M Knolle , P Knopp , C Knowles , K Knowles , L Knowles , E Knox , L Knox , O Koch , M Kocsor , R Kodituwakku , G Koduri , Y Koe , A Koirata , E Kolakaluri , M Kolodziej , E Kolokouri , S Kon , N Konar , M Kononen , A Konstantinidis , R Kontogonis , H Koo , I Koopmans , E Kopyj , L Korcierz , J Korolewicz , G Koshy , C Kosmidis , C Kosztolanyi , J Kotecha , E Kothandaraman , K Koukou , A Kountourgioti , K Kouranloo , R Kousar , M Kousteni , A Koutalopoula , M Kovac , A Kozak Eskenazia , K Krasauskas , R Krishnamurthy , V Krishnamurthy , H Krishnan , M Krishnan , N Krishnapalli , S Krizak , S Krueper , S Krupej , J Krzowski , R Kubaisi , A Kubisz-Pudelko , S Kuckreja , S Kudsk-Iversen , A Kudzinskas , C Kukadiya , N Kulkarni , A Kumar , M Kumar , R Kumar , S Kumar , V Kumar , A KundU , H Kunst , K Kupiec , A Kurani , M Kurdy , K Kuriakose , R Kurian , V Kurmars , C Kuronen-Stewart , R Kusangaya , V Kushakovsky , A Kutera , A Kuverji , A Kyei-Mensah , T Kyere-Diabour , M Kyi , N Kyi , L Kyle , K Kyriaki , J Labao , L Lacey , N Lack , M Lacson , Z Ladan , E Ladlow , H Lafferty , A Lagnado , S Laha , S Lahane , C Lai , J Lai , P Laidler , R Laing , I Laing-Faiers , E Laity , K Lake , N Lakeman , F Lalloo , A Lam , C Lam , F Lamb , L Lamb , T Lamb , P Lambert , C Lameirinhas , M Lami , H Lamont , M Lamparski , D Lamrani , C Lanaghan , I Lancona-Malcolm , G Landers , M Lane , N Lane , A Lang , S Lang , D Langer , M Langley , C Langoya , E Langridge , E Langthorne , H Langton , B Lara , T Large , S Lassa , A Last , S Latham , V Latham , A Latheef , L Latif , N Latt , C Lau , D Lau , E Lau , G Laura , M Laurenson , E Lavington , H Law , J Law , K Law , P Law , R Law , L Lawless , C Lawrence , E Lawrence , G Lawrence , H Lawrence , N Lawrence , R Lawrie , L Lawson , N Lawson , R Lawson , S Laybourne , C Laycock , R Layug , M Lazo , V Le , A Lea , W Lea , L Leach , I Leadbitter , T Leahy , R Lean , L Leandro , D Leaning , R Leary , S Leason , M Ledingham , C Lee , E Lee , H Lee , I Lee , J Lee , R Lee , S Lee , T Lee , X Lee , D Lees , J Lees , H Legge , J Leggett , K Leigh-Ellis , D Leitch , N Leitch , E Lekoudis , P Lemessy , R Lenagh , K Leng , K Lennon , L Lennon , B Leonard , K Leonard , W Leong , N Leopold , O Lepiarczyk , I Leslie , E Lester , E Levell , A Levynska , A Lewazuk , A Lewin , A Lewis , C Lewis , D Lewis , H Lewis , J Lewis , K Lewis , L Lewis , M Lewis , N Lewis , R Lewis , C Lewis-Clarke , P Lewthwaite , S Ley , A Liao , V Licence , D Lieberman , S Liebeschuetz , T Light , N Lightfoot , P Lillie , A Lillis , B Lim , C Lim , E Lim , I Lim , T Lim , W Lim , J Limb , D Limbu , U Limbu , C Linares , D Linden , G Lindergard , K Lindley , C Lindsay , E Lindsay , M Lindsay , H Lindsay-Clarke , M Ling , C Lingam , L Linkson , T Linn , M Linney , C Lippold , G Lipscomb , K Lipscomb , L Lipskis , A Lisboa , E Lister , J Little , S Little , L Littlejohn , S Liu , X Liu , D Llanera , R Llewellyn , M Llewelyn , A Lloyd , O Lloyd , R Lloyd , S Lo , D Loader , C Loan , L Lobosco , L Lock , S Lock , A Locke , J Locke , T Locke , T Lockett , J Lodge , K Lodhia , M Lofthouse , H Loftus , C A Logue , S Loh , S Lokanathan , E London , G Long , N Long , K Longbotttom , B Longhurst , M Longshaw , S Longstaffe , A Lonita , J Lonnen , C Lonsdale , L Looby , R Loosley , L Lopes , P Lopez , R Lord , S Lord , C Lorimer , F Loro , R Lorusso , C Loughlin , W Lovegrove , R Loveless , M Lovell , A Loverdou , A Low , J Low , S Low , A Lowe , C Lowe , E Lowe , F Lowe , L Lowe , M Lowe , R Lowsby , V Lowthorpe , G Lubimbi , A Lubina Solomon , G Lucas , J Lucas , A Lucey , O Lucey , S Luck , L Lui , A Luintel , H Luke , J Luke , N Lungu , A Lunia , M Luscombe , J Luveta , C Luximon , K Lwin , M Lwin , A Lye , B Lyell , E Lyka , A Lynas , C Lynch , D Lynch , S Lynch , R Maamari , H Mabb , L Mabelin , G Mabeza , J Macaro , K Macconaill , C Macdonald , A Macduff , C Macfadyen , J Macfarlane , L Macfarlane , I Macharia , L MacInnes , I MacIntyre , J MacIntyre , K Mack , C Mackay , E Mackay , L Mackay , A Mackenzie , M Mackenzie , R MacKenzie Ross , A Mackey , F Mackie , J Mackie , R Mackie , C Mackinlay , C Mackintosh , K Mackintosh , M MacLeod , S Macleod , H Maclom , M Macmahon , A MacNair , C Macphee , I Macpherson , C Macrae , A MacRaild , A Madden , M Madden , C Madden-McKee , S Maddison , N Madeja , P Madhivathanan , M Madhusudhana , A Madu , L Madziva , N Magee , F Magezi , N Maghsoodi , C Magier , L Magnaye , M Magriplis , M Magtalas , N Mahabir , S Mahadevan-Bava , A Maharajh , A Mahaveer , B Mahay , K Mahay , A Mahdi , H Mahdi , N Mahdi , T Mahendiran , S Mahendran , S Maher , A Maheswaran , S Maheswaran , T Maheswaran , P Mahjoob-Afag , A Mahmood , F Mahmood , H Mahmood , W Mahmood , Z Mahmood , H Mahmoud , M Mahmud , E Mahony , T Mahungu , L Mair , T Majekdunmi , K Majid , A Major , R Major , J Majumdar , M Majumder , T Mak , A Makan , E Makanju , S Makin , W-O Makinde , Y Makkeyah , M Malanca , F Malein , N Malhan , A Malicka , A Malik , G Malik , M Maljk , P Mallett , P Mallinder , G Mallison , L Mallon , E Malone , G Maloney , M Mamman , I Man , K Man , R Mancinelli , M Mancuso-Marcello , S Mandal , T Manders , L Manderson , J Mandeville , T Mane , R Manhas , C Maniero , R Manikonda , I Manjra , R Mankiewitz , B Mann , J Manning , S Manning , P Mannion , K Mansi , K Manso , D Mansour , M Mansour , R Mansour , I Mapfunde , P Mappa , A Maqsood , H Maraj , C Marchand , N Marcus , A Marcyniuk , M Marecka , D Maren , G Margabanthu , J Margalef , L Margarit , G Margaritopoulos , M Margarson , F Maria del Rocio , V Mariano , A Maric , G Markham , B Marks , M Marks , P Marks , E Marler , E Marouzet , A Marriott , C Marriott , N Marriott , C Marsden , K Marsden , P Marsden , S Marsden , T Marsden , C Marsh , G Marsh , R Marsh , A Marshall , G Marshall , H Marshall , J Marshall , N Marshall , R Marshall , S Marshall , E Martin , G Martin , H Martin , J Martin , K Martin , L Martin , M Martin , N Martin , S Martin , T Martin , W Martin , T Martindale , M Martineau , L Martinez , J Martinez Garrido , J Martin-Lazaro , V Maruthamuthu , B Marwan , G Maryan , R Mary-Genetu , S Maryosh , V Masani , A Mascagni , D Maseda , Z Maseko , S Mashate , Y Mashhoudi , A Mashta , I Masih , S Masih , N Maskell , P Maskell , M Masoli , C Mason , J Mason , R Mason , M Masood , S Masood , T Massa , I Massey , J Masters , A Masud , L Matapure , C Matei , R Matewe , M Matharu , S Mathen , A Mather , J Mathers , J Matheson , A Mathew , B Mathew , M Mathew , V Mathew , J Mathews , K Mathias , A Mathioudakis , D Matila , W Matimba-Mupaya , N Matin , E Matisa , E Matkins , M Matonhodze , E Matovu , J Mattappillil , A Matthews , C Matthews , H Matthews , L Mattocks , C Maughan , A Mauzzam , E Mawson , F Maxton , A Maxwell , V Maxwell , J May , P May , E May , I Mayanagao , M Maycock , J Mayer , G Mayers , V Maynard , T Mayo , L Mayola , S Mayor , I Mazen , T Mazhani , A Mazzella , N Mburu , A Mbuyisha , C Mc Cague , E McAleese , P McAlinden , L McAllister , A McAlpine , G McAlpine , J McAndrew , H McAuley , S McAuliffe , C McBrearty , E McBride , M McBuigan , J McBurney , L McCabe , G McCafferty , L McCafferty , A McCairn , L McCallagh , J McCammon , N McCammon , C McCann , E McCann , A McCarrick , B McCarron , E McCarthy , M McCarthy , N McCarthy , S McCaughey , T McClay , B McClelland , D McClintock , M McCloskey , K McCollum , A McCorkindale , P McCormack , J McCormick , W McCormick , P McCourt , J McCrae , S McCready , G McCreath , H McCreedy , C McCue , I McCullagh , M McCullagh , S McCullough , C McCullough , K McCullough , N McCullough , F McCurrach , J McDermott , P McDermott , R McDermott , K McDevitt , H McDill , C McDonald , D McDonald , R McDonald , S McDonald , B McDonard , N McDonnell , C McDougall , L McDougall , R McDougall , I McEleavy , F McElwaine , J McEntee , E McEvoy , C McEwan , R McEwen , M McFadden , D McFarland , M McFarland , R McFarland , J McFlynn , E McGarry , L McGarvey , A McGeachan , F McGee , L McGenily , C McGettigan , M McGettrick , C McGhee , F McGill , S McGinnity , N McGlinchey , P McGlone , D McGlynn , C McGoldrick , E McGough , C McGovern , R McGovern , A McGowan , A McGown , B McGrath , A McGregor , M McGuigan , H McGuinness , S McGuire , T McHugh , C McInnes , N McInnes , J McIntosh , K McIntyre , M McIntyre , L McKay , C McKeag , J McKeane , M McKee , J McKeever , J McKenna , S McKenna , M McKenzie , D McKeogh , C McKerr , L Mckie , A McKie , H Mckie , G McKnight , H McLachlan , A McLaren , B McLaren , N McLarty , E Mclaughlan , M McLaughlin , J McLay , M McLeish , T McLennan , S McLure , A McMahon , G McMahon , M McMahon , S McMahon , T McManus , P McMaster , M McMaster , F Mcmeeken , S McMeekin , K McMillen , J McMinn , L McMorrow , H McMullen , C McMurran , H McNally , F McNeela , L McNeil , C McNeill , J McNeill , S McNeill , U McNelis , M McNulty , R McNulty , C McParland , M McPhail , A McQueen , A McSkeane , D McSorland , T McSorley , J McTaggart , G McTaggart , J Mead , P Mead , E Meadows , O Meakin , B Mearns , C Mearns , K Mears , W Mears , M Meda , A Mediana , R Medine , T Medveczky , S Meehan , E Meeks , A Megan , N Meghani , S Meghjee , S Megson , A Mehar , M Mehmood , R Mehra , R Mehta , J Meirill , J Meiring , R Mejri , E Mekonnen , S Melander , A Melinte , J Mellersh , L Melling , C Mellish , F Mellor , J Mellor , S Mellor , Z Mellor , K Mellows , V Melnic , A Melville , D Melville , J Melville , M Mencias , A Mendelski , C Mendonca , C Meney , W Mensah , A Mentzer , D Menzies , S Menzies , S Mepham , O Mercer , P Mercer , A Merchant , F Merchant , M Mercioniu , M Meredith , M Merida Morillas , B Merrick , J Merritt , S Merritt , P Merron , E Merwaha , S Message , J Messenger , G Metcalf-Cuenca , A Metcalfe , B Metcalfe , K Metcalfe , S Metherell , A Metryka , L Mew , S Meyrick , A Miah , J Miah , N Miah , A Mian , G Mic , D Micallef , A Michael , S Michael , N Michalak , L Michalca-Mason , O Michalec , J Middle , H Middleton , J Middleton , M Middleton , S Middleton , S Mieres , L Mihalca-Mason , T Mikolasch , S Milgate , C Millar , J Millar , J Millard , D Miller , J Miller , L Miller , R Miller , N Miller-Biot , A Miller-Fik , L Millett , B Milligan , H Milligan , I Milligan , C Milliken , K Millington , R Millington , S Millington , H Mills , J Mills , R Mills , H Millward , R Miln , A Milne , C Milne , L Milne , J Milner , L Milner , Z Min , S Mindel , C Minnis , P Minnis , K Minou , N Minskip , J Minton , F Miranda , M Mirela , T Mirza , A Misbahuddin , E Mishr , A Mishra , B Mishra , R Mishra , S Misra , D Mistry , H Mistry , D Mital , S Mitchard , B Mitchell , C Mitchell , L Mitchell , P Mitchell , P Mitchelmore , A Mitr , S Mitra , N Mlambo , E Moakes , K Moar , E Moatt , D Mock Font , G Modgil , A Mohamed , O Mohamed , A Mohammad , W Mohammad , A Mohammed , O Mohammed , Y Mohammed , B Mohamud , A Moharram , H-P Mok , J Mok , L Mokogwu , M Molina , C Moller-Christensen , M Mollet , M Molloholli , A Molloy , L Molloy , A Molyneux , R Molyneux , T Momoniat , K Monaghan , S Mongolu , K Monsell , M Montasser , H Montgomery , P Moodley , M Moody , N Moody , A Moon , J Moon , M Moon , M Moonan , P Moondi , S Moorby , J Moorcroft , A Moore , C Moore , D Moore , F Moore , J Moore , L Moore , N Moore , S Moore , V Moore , R Moores , E Morab , J Morales , N Moramorell , L Moran , G Moray , J Moreno-Cuest , A Morgan , C Morgan , H Morgan , K Morgan , L Morgan , M Morgan , P Morgan , K Morgan-Jones , E Morgan-Smith , J Morilla , A Morley , T Morley , W Morley , A Morris , D Morris , F Morris , H Morris , J Morris , K Morris , L Morris , M Morris , N Morris , P Morris , S Morris , D Morrison , M Morrison , S Morrison , M Morrissey , A Morrow , F Morselli , G Mortem , V Mortland , C Morton , G Morton , P Morzaria , D Mosby , L Moseley , K Moshal , B Moshy , A Moss , C Moss , J Moss , S Moss , O Mostafa , G Moth , N Motherwell , S Mottershaw , G Mouce , H Moudgil , J Mouland , C Moulds , H Moulton , E Mousley , C Mowatt , K Moxham , B Moya , Q Moyo , E Mshengu , S Mtuwa , I Muazzam , N Muchenje , D Mudawi , G Muddegowda , R Mufti , I Mugal , A Mughal , J Muglu , F Muhammad , J Muhammad , C Muir , D Mukherjee , J Mukhtar , S Mukhtar , D Mukimbiri , J Mulcahy , M Mulcahy , P Mulgrew , B Mulhearn , A Mulla , D Mullan , D Mullasseril Kutten , N Mulle , R Mullett , C Mulligan , S Mulligan , L Mumelj , H Munby , H Munday , A Munro , S Munt , M Mupudzi , A Murad , O Muraina , K Muralidhara , M Murdoch , J Murira , A Murphy , B Murphy , C Murphy , E Murphy , G Murphy , H Murphy , P Murphy , R Murphy , S Murphy , D Murray , E Murray , K Murray , L Murray , T Murray , E Murtagh , M Murthy , C Murton , R Murton , N Muru , R Musanhu , M Mushabe , O Mushtaq , A Mustafa , E Mustafa , M Mustafa , I Mustapha , N Mustfa , Z Mustufvi , C Mutch , R Mutch , E Mutema , B Muthukrishnan , S Mutton , M Mwadeyi , B Mwale , E Mwaura , R Myagerimath , A Myers , S Myers , J Myerson , K Myint , Y Myint , G Mynott , L Myslivecek , Z N Oo , P Nabayego , E Nadar , I Nadeem , M Nadheem , B Nadjm , A Naeem , H Naeem , S Naeem , S Nafees , M Nafei , T Nagarajan , L Naglik , I Nagra , D Nagra , M Naguib , K Naguleswaran , K Nagumantry , K Naicker , S Naidoo , D Nair , G Naik , R Naik , S Naik , T Nair , J Naisbitt , K Naismith , D Nakiboneka-Ssenabulya , S Nallapareddy , S Nallapeta , A Nallasivan , U Nand , A Nandani , T Nandwani , A Naqvi , S Naqvi , S Nasa , D Nash , N Nasheed , A Nasimudeen , U Nasir , T Nasser , A Natarajan , G Natarajan , N Natarajan , R Natarajan , P Nath , N Nathaniel , M Nathvani , P Nathwani , G Nava , N Navaneetham , J Navaratnam , H Navarra , S Naveed , J Navin , K Nawaz , S Nawaz , B Nayar , S Naylor , M Nayyar , F Naz , B Nazari , A Nazir , S Nazir , D Ncomanzi , O Ndefo , N Ndoumbe , A Neal , E Neary , M Negmeldin , L Nei , J Neil , P Neill , H Neils , A Nejad , A Nelson , B Nelson , L Nelson , M Nelson , R Nelson , S Nelson , R Nemane , S Nepal , D Nethercott , K Netherton , K Nettleton , A Newby , D Newby , T Newcombe , H Newell , C Newman , D Newman , H Newman , J Newman , O Newman , T Newman , R Newport , M Newton , A Ng , H Ng , K Ng , M Ng , W Ng , Y Ng , T Ngan , G Ngui , S Ngumo , Q Nguyen , K Ngwenya , C Nic Fhogartaigh , N Nicholas , P Nicholas , R Nicholas , D Nicholls , L Nicholls , S Nicholls , A Nicholson , E Nicol , R Nicol , P Nicola , A Nicoll , T Nightingale , F Nikita , P Nikolaos , G Nikonovich , A Nilsson , K Nimako , L Nimako , C Nimmo , P Ninan , M Nirmalan , A Nisar , M Nisar , T Nisar , T Nisbett , A Nisha James , S Nishat , T Nishiyama , S Nix , J Nixon , M Nixon , K Nizam Ud Din , M Nizami , S Nizamis , R Njafuh , I Noakes , L Noba , H Noble , J Noble , H Noe , J Nolan , J Nolasco , Z Noor , Z Noori , J Norcliffe , L Norman , R Norman , E Norris , K Norris , L Norris , J Nort e , S Nortcliffe , F North , J North , T North , J Northfield , S Northover , D Norton , R Norton , H Notman , K Nourein , T Novak , N Novas Duarte , C Novis , J Nowak , K Nu , M Nugdallah , A Nugent , J Nugent , N Numbere , K Nundlall , A Nune , K Nunn , J Nunnick , Y Nupa , F Nur , Z Nurgat , A Nuttall , L Nwafor , P Nwajiugo , G Nyamugunduru , M Nyirenda , K Nyland , D O Rinn , D O Shea , M O Toole , M O'Hara , L O'Keefe , K O'Reilly , W O'Rourke , C Oakley , N Oakley , S Oakley , B Obale , C Oboh , C O'Brien , J O'Brien , K O'Brien , L O'Brien , N O'Brien , R O'Brien , T O'Brien , E O'Bryan , R Obukofe , C O'Callaghan , L O'Connell , C O'Connor , G O'Connor , T Oconnor , M Odam , S Oddie , S Oddy , Y Odedina , K Odedra , S Odelberg , N Odell , O Oderinde , J Odone , L O'Donohoe , C O'Donovan , I Odysseos-Beaumont , S O'Farrell , P Offord , M O'Flaherty , T Ogbara , C Ogilvie , C O'Gorman , I Ogunjembola , O Ogunkeye , C O'Hara , S Ojha , O Ojo , F O'kane , M O'Kane , T Okeke , A Okines , I Okpala , E Okpo , F Okpoko , M Okubanjo , C Oladipo , L Olaivar , R Olaiya , J Olatujoye , T Old , G Oleszkiewicz , C Oliver , J Oliver , L Oliver , M Oliver , Z Oliver , N Olokoto , F Olonipile , O Olufuwa , O Olukoya , A Oluwole-Ojo , L O'Malley , M Omar , Z Omar , N Omer , E Omoregie , C O'Neill , L O'Neill , C Ong , O Onuoha , C Onyeagor , C Oo , S Ooi , A Oomatia , M Opena , R Oram , C Ord , J Ord , C Oreilly , L Orekoya , D O'Riordan , S O'Riordan , I Orlikowska , A Orme , H Orme , L O'Rourke , C Orr , S Orr , C Orton , A Osadcow , R Osagie , R Osanlou , L Osborne , N Osborne , W Osborne , C Osbourne , R Osbourne , J Osei-Bobie , B Osman , J Osman , W Osman , G Osoata , M Ostermann , E O'Sullivan , S O'Sullivan , N Otey , O Otite , J Ouyang , R Owen , S Owen , E Owens , Y Owoseni , M Owston , R Oxlade , F Ozdes , J Pack , A Packham , S Packham , P Paczko , G Padden , A Padmakumar , C Page , I Page , I Page , J Page , S Page , V Page , J Paget , K Pagett , L Paisley , S Pajak , G Pakou , A Pakozdi , S Pal , A Palacios , V Palagiri Sai , V Palaniappan , P Palanivelu , A Palfreeman , H Palfrey , V Palissery , D Palit , S Pallipparambil Antony , J Palman , A Palmer , H Palmer , J Palmer , L Palmer , R Palmer , A Pambouka , D Pamela , I Pamphlett , D Pan , A Pandey , N Pandian , K Pandya , T Pandya , A Panes , J Pang , Y Pang , L Pannell , 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Pattrick , M Paul , S Paul , L Pauls , S Paulus , A Pavely , M Pavitt , B Payne , E Payne , M Payne , R Payne , L Peacock , S Peacock , H Peake , J Pearce , R Pearse , A Pearson , D Pearson , H Pearson , S Pearson , S Pearson , A Peasley , H Peddie , S Peebles , R Peek , A Peer , S Peerbhoy , C Pegg , E Peggie , H Peggie , S Peglar , B Peirce , M Peirse , C Pelham , A Pemberton , M Penacerrada , A Pender , C Pendlebury , J Pendlebury , R Penfold , C Penman , J Penman , R Penman , J Penner , K Penney , A Pennington , J Penny , J Pepperell , R Percival , A Pereira , R Pereira , C Pereira Dias Alves , I Perera , M Perera , E Perez , J Perez , T Perinpanathan , L Periyasamy , E Perkins , I Pernicova , E Perritt , A Perry , E Perry , M Perry , T Perumpral , R Petch , L Peter , C Peters , L Peters , M Peters , S Peters , T Peters , R Petersen , A Peterson , I Petras , B Petrova , M Petrova , E Petrovics , T Pettigrew , M Pezard-Snell , P Pfeffer , T Maria Pfyl , G Phalod , M Phanish , P Phelan , C Philbey , J Philbin , A Phillips , B Phillips , D Phillips , N Phillips , P Phillips , R Phillips , T Phillips , M Phipps , V Phongsathorn , M Phull , A Phyo , S Pick , J Pickard , C Pickering , F Pickering , G Pickering , T Pickett , J Pickles , S Pickstock , B Pickwell-Smith , N Pieniazek , C Piercy , A Pieris , S Pilgrim , P Pillai , L Pilling , Z Pilsworth , S Pinches , M Pinjala , S Pintu , G Piper , T Pirani , M Pitchford , M Pittman , S Pitts , M Pl , N Plaatjies , N Platt , M Plowright , L Plummer , C Plumptre , J Pobjoy , T Pogreban , S Poku , P Polgarova , R Pollard , O Poluyi , G Polwarth , F Pomery , I Ponce , P Ponnusamy , S Ponnusamy , A Ponnuswamy , I Ponte Bettencourt dos Reis , S Pooboni , A Poole , L Poole , M Poole , S Poon , T Poonian , J Porteous , M Porteous , D Porter , J Porter , R Porter , A Posada , K Postlethwaite , M Potdar , C Pothecary , N Pothina , P Potla , D Potoczna , J Pott , A Potter , J Potter , S Potter , T Potter , E Potton , J Potts , 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Pyart , E Pye , M Pynn , T Qadeer , M Qayum , C Quah , S Quaid , N Quail , C Quamina , G Quartermaine , T Quasim , A Quayle , E Quek , S Quenby , X Qui , J Qui ano-Campos , V Quick , J Quigley , J Quindoyos , A Quinn , J Quinn , T Quinn , Q Quratulain , D Qureshi , E Qureshi , H Qureshi , I Qureshi , K Qureshi , N Qureshi , Q Qurratulain , S Qutab , A R Naqvi , J Ra eswary , J Ra kanna , S Rabinowicz , M Raceala , A Rachid , R Rachman , L Rad , L Radford , J Radford , J Radhakrishnan , H Rafferty , M Rafiq , S Rafiq , C Rafique , J Rafique , M Rafique , R Ragatha , A Raghunathan , A Raguro , S Raha , S Rahama , K Rahilly , F Rahim , A Rahimi , H Rahimi , M Rahman , S Rahman , S Rahmany , P Rai , S Rai , L Raisova , A Raithatha , A Raj , A Rajagopal , P Rajagopalan , N Rajaiah , K Rajalingam , A Rajasekaran , A Rajasri , T Rajeswaran , I Rajkumar , G Rajmohan , R Rallan , M Ralson , K Ralston , M Ralston , M Ram , B Ramabhadran , F Ramali , M Ramali , S Ramanna , M Ramasamy , A Ramchandani , D Ramdin , J Ramirez , M Ramirez , G Ramnarain , A Ramnarine , L Ramos , T Rampling , S Ramraj , J Ramsay , A Ramshaw , A Rand , G Rana , J Rand , N Rana , R Rana , H Randheva , P Ranga , M Rangar , H Rangarajan , S Ranjan , H Rank , P Ranka , R Rankhelawon , A Rankin , A Rao , D Rao , S Rao , A Rarnakumar , A Rasheed , K Rashid , M Rason , V Raspa , S Rastogi , F Rasul , S Ratcliff , S Ratcliffe , P Rath , S Rath , M Rather , K Rathod , S Rathore , J Ratoff , D Rattehalli , D Ravaccia , M Raval , P Ravencroft , J Raw , R Raw , S Rawashdeh , H Rawlins , G Ray , A Raymond-White , D Raynard , H Rayner , N Rayner , A Raynsford , S Razvi , Z Razvi , K Read , S Read , M Reay , A Reddington , A Reddy , H Reddy , H Redfearn , A Redfern-Walsh , I Redknap , N Redman , A Redome , J Redome , A Reed , J Reed , C Rees , J Rees , M Rees , S Rees , T Rees , E Rees-Jones , F Regan , K Regan , M Regan , S Regan , K Rege , A Rehan , A Rehman , H Rehman , S Rehman , Z Rehman , A Reid , J Reid , S Reid , M Reilly , S Reilly , A Reka , A Remegoso , D Rengan , L Renouf , C Renshaw , R Renu Vattekkat , J Renville , H Reschreiter , M Revels , A Revill , G Rewitzky , S Rey , C Reynard , D Reynish , H Reynolds , P Reynolds , J Rhodes , N Riaz , P Ribeiro , E Rice , M Rice , N Rice , M Rich , A Richards , L Richards , S Richards , C Richardson , E Richardson , F Richardson , J Richardson , M Richardson , N Richardson , J Riches , K Riches , L Richmond , R Richmond , W Ricketts , H Rickman , A Riddell , S Ridgway , M Ridha , C Ridley , P Ridley , G Rieck , L Rigby , M Rigby , D Rigler , H Riley , M Riley , R Riley , Z Rimba , D Rimmer , R Rintoul , D Ripley , N Rippon , C Rishton , M Riste , D Ritchie , J Ritchie , A Ritchings , P Rivera Ortega , V Rivers , B Rizvi , S Rizvi , J Robb , E Robbins , G Roberts , J Roberts , K Roberts , M Roberts , N Roberts , P Roberts , R Roberts , V Roberts , C Robertson , J Robertson , K Robertson , M Robertson , N Robertson , S Robertson , N Robin , A Robinson , C Robinson , E Robinson , G Robinson , H Robinson , J Robinson , K Robinson , L Robinson , M Robinson , N Robinson , R Robinson , S Robinson , S Robson , L Roche , S Roche , N Rodden , E Roddy , J Roddy , M Roderick , A Rodger , F Rodger , M Rodger , D Rodgers , N Rodgers , R Rodriquez-Belmonte , N Roe , G Rogers , J Rogers , L Rogers , M Rogers , P Rogers , S Rogers , J Rojkova , S Rokadiya , L Rollins , J Rollo , C Rolls , A Rond-Alliston , K Rooney , L Rooney , L Rosaroso , E Rosby , A Rose , S Rose , Z Rose , J Rosier , A Roskilly , G Ross , I Ross , J Ross , J Rossdale , A Ross-Parker , A Rostron , A Rothman , J Rothwell , L Roughley , C Rourke , N Rowan , S Rowan , A Rowe , N Rowe , L Rowe-Leete , E Rowlands , B Rowlands , M Rowley , S Roy , M Roycroft , A Roynon-Reed , A Royson , S Rozewicz , A Rudenko , S Rudrakumar , B Rudran , S Ruff , P Rughani , R Rule , S Rundell , E Rushforth , J Rushmer , D Rusk , P Russell , R Russell , C Russo , M Rutgers , K Rutkowski , A Ryan , B Ryan , K Ryan , L Ryan , M Ryan , P Ryan , D Ryan-Wakeling , E Rybka , M Ryder , S Ryder , M S Bhuiyan , M S Rabbani , M Saad , G Saalmink , J Sabale , S Sabaretnam , N Sadiq , E Sadler , A Saffy , B Sage , H Sagoo , S Sagrir , R Saha , S Saha , N Sahdev , S Sahedra , J Sahota , N Said , S Saini , B Saint , A Sajid , S Sakthi , H Sakuri , M Saladi , A Salam , A Salberg , E Salciute , G Saleeb , M Saleh , L Salih , D Salim , S Salisbury , S Saliu , R Salman , R Salmon , J Salmon , D Salutous , M Sam , T Samakomva , R Saman , S Samar , S Saminathan , R Samlal , D Sammut , M Sammut , S Sammut , T Sammut , S Sampath , C Sampson , J Sampson , A Samson , J Samuel , M Samuel , R Samuel , T Samuel , Y Samuel , K Samuels , T Samuels , J Samways , M Samyraju , I Sana , A Sanches Gonzalez , V Sanchez , A Sanda-Gomez , J Sanders , A Sanderson , T Sanderson , K Sandhu , L Sandhu , S Sandow , V Sandrey , S Sands , L Sanga , H Sangha , J Sanghera , M Sangombe , M Sanju , L Sankaran , F Santos , C Santos FerreirDe Almeida , R Santosh , J Sanyal , A Sanz-Cepero , D Saralaya , A Saraswatula , P Saravanamuthu , J Sarella , A Sarfatti , R Sargent , B Sari , K Sarkar , R Sarkar , S Sarma , P Sarmiento , Z Sarwar , T Sass , K Satchithananthasivam , S Sathe , S Sathianandan , A Sathyanarayanan , L Sathyanarayanan , T Sathyapalan , P Satodia , V Saulite , A Saunders , R Saunders , S Saunders , A Saunderson , H Savill , K Savlani , G Saxena , M Saxton , A Sayan , I Sayers , D Scaletta , D Scanlon , J Scanlon , L Scarratt , S Scattergood , A Schadenberg , J Schafers , W Schneblen , E Schofield , R Schofield , S Schofield , D Scholes , K Scholes , A Schoolmeesters , N Schumacher , N Schunke , M Schuster Bruce , K Schwarz , A Scobie , T Scoones , T Scorrer , A Scott , C Scott , E Scott , K Scott , L Scott , M Scott , S Scott , T Scott , Z Scott , S Scourfield , W Scrase , N Scriven , A Scullion , T Scullion , E Seager , C Seagrave , R Seaman , E Sear , I Seaton , A Seatter , A Seckington , J Sedano , G Seddon , G Sedgwick , Y See , M Seelarbokus , C Sefton , M Segovia , F Seidu , G Sekadde , F Selby , G Selby , C Sellar , R Sellars , K Sellers , J Selley , V Sellick , G Selvadurai , B Selvarajah , H Selvaskandan , S Selvendran , J Selwyn , A Semmens , G Semple , N Sen , M Sen , S Sen , A Sengupta , N Sengupta , S Senra , H Senya , T Serafimova , E Sernicola , D Sethi , S Sethi , N Setty , A Seward , T Sewdin , T Sewell , J Seymour , K Seymour , H Shabbir , F Shackley , T Shafi , F Shafique , A Shah , B Shah , H Shah , M Shah , N Shah , P Shah , Q Shah , R Shah , S Shah , W Shah , S Shahad , S Shahi , S Shahnazari , N Shahzad , M Shahzeb , A Shaibu , Z Shaida , A Shaikh , M Shaikh , R Shail , M Shaji , M Shakeel , K Shalan , N Shamim , U Shamji , A Shams , K Shams , R Shamsah , T Shanahan , H Sharaf , A Sharif , A Sharma , B Sharma , M Sharma , O Sharma , P Sharma , R Sharma , S Sharma , A Sharp , C Sharp , G Sharp , K Sharp , L Sharp , P Sharratt , K Sharrocks , S Shashaa , A Shaw , C Shaw , D Shaw , J Shaw , L Shaw , M Shaw , T Shaw , A Shawcross , J Shawcross , J Shawe , L Shayler , S Shedwell , Z Shehata , A Sheik , A Sheikh , N Sheikh , B Shelley , S Shelton , A Shenoy , S Shephardson , A Shepherd , G Sheppard , K Shepherd , L Shepherd , S Shepherd , R Sheppeard , H Sheridan , R Sheridan , S Sherridan , L Sherris , S Sherwin , S Shibly , F Shiham , C Shilladay , B Shillitoe , D Shingadia , C Shioi , A Shirgaonkar , H Shirt , A Shonubi , J Shoote , R Shorrocks , R Shortman , R Shotton , S Shotton , C Shovelton , E Shpuza , N Shrestha , K Shuker , J Shurlock , J Shurmer , M Shuvo , G Siame , L Siamia , S Siddavaram , N Siddique , S Siddique , E Siddle , E Sidebotham , J Sidebottom , R Sievers , K Siggens , N Sikondari , S Silva , C Silva Moniz , M Sim , T Simangan , V Simbi , R Sime , G Simmons , O Simmons , R Simms , L Simon , M Simon , N Simon , S Simpkins , A Simpson , D Simpson , G Simpson , J Simpson , K Simpson , M Simpson , P Simpson , T Simpson , D Sinclair , C Sing , A Singh , C Singh , D Singh , J Singh , L Singh , M Singh , N Singh , P Singh , S Singh , P Singhal , B Singizi , V Singler , M Sinh , U Sinha , P Sinha , S Sinha , G Sisson , S Sithiravel , K Sivakumar , S Sivakumar , D Sivakumran , S Sivanadarajah , P Sivasothy , A Skaria , N Skehan , R Skelly , O Skelton , I Skene , V Skinner , D Skinner , A Skorko , I Skorupinska , M Skorupinska , A Slack , K Slack , M Slade , L Slater , N Slawson , R Slingsby , A Sloan , B Sloan , D Sloan , G Sloane , M Slowinska , B Small , E Small , S Small , A Smallridge , D Smalls , K Smallshaw , A Smallwood , B Smart , L Smart , J Smeaton , C Smit , A Smith , C Smith , D Smith , E Smith , H Smith , I Smith , J Smith , K Smith , L Smith , M Smith , N Smith , O Smith , P Smith , R Smith , S Smith , T Smith , V Smith , S Smolen , S Smuts , N Smyth , A Snell , D Snell , L Snell , A So , B So , M Soan , T Sobande , S Sobowiec Kouman , A Sobrino Diaz , B Sohail , H Sohal , R Soiz , O Solademi , B Soleimani , A Solesbury , M Soliman , B Solis , R Solly , L Solomon , S Somalanka , C Somashekar , S Sommerfield , G Soni , R Sonia , T Sonoiki , S Soo , P Soor , G Soothill , J Soren , A Sothinathan , P Sothirajah , J Sousa , N Soussi , D Southam , D Southern , I Southern , L Southern , S Southin , J Southwell , T Southworth , S Sowden , J Sowter , C Spalding , C Speare , K Spears , M Spears , L Speirs , S Speirs , M Spence , N Spence , B Spencer , G Spencer , R Spencer , S Spencer , T Spencer , H Spickett , J Spillane , W Spiller , K Spinks , M Spinks , N Spittle , S Spray , O Spring , J Springgs , G Squires , J Squires , R Squires , R Sreenivasan , S Sreenivasan , K Sri Paranthamen , R Srikantaiah , K Srinivasan , R Srinivasan , A Srirajamadhuveeti , V Srirathan , R Stacey , S Stacpoole , L Stadon , W Stagg , J Staines , N Staines , K Stammers , R Stanciu , G Stanczuk , T Standley , B Staniforth , A Stanton , L Stanton , R Staples , S Stapley , A Stark , E Starkey , D Starnes , M Starr , R Stead , C Stebbing , C Steele , H Steer , J Steer , V Stefania , P Stefanowska , F Steffensen , C Stemp , E Stenson , A Stephens , D Stephensen , E Stephenson , M Sterrenburg , J Stevens , M Stevens , A Stevenson , L Stevenson , S Stevenson , M Steward , C Stewart , D Stewart , K Stewart , M Stewart , R Stewart , J Stickley , G Stiller , S Stirrup , S Stock , A Stockdale , D Stocker , L Stockham , P Stockton , E Stoddard , C Stokes , B Stone , R Stone , S Stone , I Storey , K Storton , F Stourton , A Strachan , C Strait , E Stratton , J Stratton , S Straw , D Streit , E Stride , S Stringer , S Strong-Sheldrake , S Struik , C Stuart , A Stubbs , H Stubbs , A Sturdy , S Sturney , M Stuttard , C Suarez , K Subba , C Subbe , K Subramaniam , M Subramanian , V Subramanian , C Subudhi , R Suckling , S Sudershan , P Sugden , R Sukla , A Sukumara , E Suleiman , A Suliman , F Suliman , S Sultan , S Sundar , R Sundaram , R Sundhar , E Sung , 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, S Tavares , V Tavoukjian , A Taylor , B Taylor , C Taylor , D Taylor , E Taylor , H Taylor , J Taylor , L Taylor , M Taylor , N Taylor , R Taylor , S Taylor , T Taylor , V Taylor , M Taylor-Siddons , T Taynton , A Te , F Teasdale , J Teasdale , K Teasdale , J Tebbutt , C Tee , I Teeluck , B Tejero Moya , R Tejwani , A Telfer , V Teli , J Tempany , J Temple , N Temple , H Tench , Y Teoh , R Tereszkowski-Kaminski , L Terrett , L Terry , D Tetla , S Tewari , D Tewkesbury , J Texeira , C Tey , M Thake , C Thakker , M Thakker , J Thakrar , B Thamu , H Thatcher , A Thayanandan , K Thazhatheyil , E Thein , L Theocharidou , P Thet , K Thevarajah , M Thevendra , N Thiri Phoo , Y Thirlwall , M Thirumaran , A Thomas , C Thomas , E Thomas , H Thomas , J Thomas , K Thomas , L Thomas , R Thomas , S Thomas , T Thomas , V Thomas , K Thomasson , R Thomas-Turner , C Thompson , E Thompson , F Thompson , H Thompson , J Thompson , K Thompson , L Thompson , M Thompson , O Thompson , R Thompson , Y Thompson , N Thomson , P Thorburn , N Thorn , C Thorne , N Thorne , A Thornton , D Thornton , J Thornton , R Thornton , S Thornton , T Thornton , S Thorpe , C Thorpe , N Thorpe , P Thozthumparambil , L Thrasyvoulou , H Thraves , G Thueux , P Thu-Ta , V Thwaiotes , S Tiberi , S Tieger , C Tierney , M Tighe , S Tilbey , C Till , A Tiller , H Tiller , J Timerick , E Timlick , A Timmins , A Timmis , H Timms , A Timoroksa , S Tinashe , S Tingley , N Tinker , M Tinkler , J Tipper , A Tirumalai Adisesh , H Tivenan , K Tluchowska , H T-Michael , A Todd , J Todd , S Todd , O Toffoletti , M Tohfa , S Tohill , M Tolson , N Tomasova , S Tomlin , S Tomlins , J Tomlinson , K Tomlinson , J Tonkin , I Tonna , C Toohey , K Topham , M Topping , A Torokwa , C Torrance , O Touma , L Tous Sampol , R Tousis , M Tout , P Tovey , G Towersey , J Townley , R Tozer , M Tran , H Tranter , J Travers , C Travill , S Traynor , L Trethowan , E Treus Gude , M Trevelyan , N Trewick , A Tridente , S Triggs , F Trim , A Trimmings , T Trinick , K Trivedi , S Troedson , E Tropman , A Trotter , S Trous , H Trower , M Trowsdale Stannard , N Trudgill , N Truman , M Truslove , S Trussell , T Trussell , K Tsakiridou , C Tsang , P Tsang , T Tsawayo , K Tsilimpari , G Tsinaslanidis , S Tso , S Tucker , N Tucker , S Tucker , D Tudor , A Tufail , J Tuff , J Tuffney , R Tully , G Tunesi , K Turbitt , R Turel , T Turgut , C Turley , C Turley , A Turnbull , A Turner , C Turner , G Turner , K Turner , L Turner , M Turner , P Turner , S Turner , V Turner , I Turner-bone , S Turney , J Turvey , C Tweed , D Tweed , R Twemlow , E Twohey , B Tyagi , V Tyagi , A Tyer , A Tyler , J Tyler , A Tyzack , P Tzavaras , I Tzinieris , A Uddin , M Uddin , R Uddin , J Ugoji , E Ukaegbu , M Ul Haq , W Ul Hassan , Z Ul-Haq , S Ullah , J Um , A Umaipalan , A Umate , J Umeadi , A Umeh , W Umeojiako , B Ummat , E Underhill , C Underwood , J Underwood , V Uppal , G Upson , M Ur Rasool , A Uriel , S Urruela , H Uru , J Usher , M Usher , A Usher-Rea , A Ustianowski , H Uzu , L Vaccari , U Vaghela , A Vaidya , D Vail , B Valecka , J Valentine , B Valeria , P Vallabhaneni , N Vallotton , L Vamplew , E Vamvakiti , J Vamvakopoulos , L van Bruggen , M van de Venne , A van der Meer , N van der Stelt , L van Koutrik , A Van Loggerenberg , J Vance-Daniel , R Vancheeswaran , S Vandeyoon , P Vankayalapati , P Vanmali , C Vansomeren , S Vara , S Vardy , A Varghese , M Varghese , W Varney , G Varnier , A Varouxaki , R Varquez , V Vasadi , K Vassell , O Vassell , V Vasu , V Vasudevan , M Vatish , S Vaughan , H Vayalaman , D Vayapooree , C Vaz , N Veale , S Veerasamy , S Velankar , L Velauthar , N Veli , N Vella , A Velugupati , A Velusamy , I Venables , M Venditti , R Venkataramakrishnan , R Venn , L Ventilacion , J Vere , M Veres , S Vergnano , W Verling , A Verma , R Vernall , B Vernon , M Vertue , L Verueco , J Verula , N Vethanayagam , S Vettikumaran , L Veys , C Vickers , S Victor , S Victoria , J Vidler , B Vijayakumar , V Vijayaraghavan Nalini , B Vilcinskaite , A Vileito , N Vilimiene , L Vinall , S Vinay , L Vinayakarao , O Vincent , R Vincent , P Virdee , E Virgilio , A Virk , E Visentin , M Vitaglione , K Vithian , S Vittoria , S Vivekananthan , E Vlad , B Vlies , L von Oven , C Vooght , K Vutipongsatorn , A Vuylsteke , E Vyras , A W Hay , R Wach , B Wadams , S Wadd , N Waddington , P Wade , J Wadsley , K Wadsworth , S Wafa , D Wagstaff , L Wagstaff , D Wahab , Z Wahbi , A Waheed Adigun , S Waidyanatha , A Waite , R Wake , A Wakefield , W Wakeford , F Wakinshaw , E Waldeck , A Walden , L Walding , A Waldron , J Waldron , E Wales , B Wali , D Walker , G Walker , H Walker , I Walker , K Walker , L Walker , O Walker , R Walker , S Walker , G Wallace , R Wallbutton , J Wallen , A Waller , R Waller , G Wallis , L Wallis , M Wallis , E Walmsley , D Walsh , E Walsh , L Walsh , D Walstow , D Walter , A Walters , H Walters , J Walters , E Walton , L Walton , M Walton , O Walton , S Walton , M Wands , R Wane , F Wang , N Wang , R Wang , S Wang , D Warbrick , S Warburton , C Ward , D Ward , E Ward , H Ward , J Ward , L Ward , N Ward , R Ward , T Ward , S Warden , G Wardere , S Wardle , H Wardy , G Waring , S Waring , B Warner , C Warner , L Warnock , S Warran , J Warren , L Warren , R Warren , Y Warren , D Warrender , H Warren-Miell , G Warwick , H Wassall , E Wasson , E Wastson , H Watchorn , H Waterfall , A Waters , D Waters , M Waterstone , A Watkin , C Watkins , E Watkins , K Watkins , L Watkins , A Watson , E Watson , F Watson , J Watson , K Watson , L Watson , P Watson , R Watson , M Watters , D Watterson , D Watts , J Watts , M Watts , V Waugh , E Wayman , M Wayman , A Wazir , M Weatherhead , N Weatherly , C Webb , H Webb , K Webb , S Webb , C Websdale , D Webster , I Webster , J Webster , T Webster , J Wedlin , L Wee , R Weerakoon , T Weerasinghe , J Weeratunga , M Weetman , S Wei , I Weichert , E Welch , H Welch , L Welch , S Welch , B Welham , S Weller , L Wellings , B Wells , S Wellstead , B Welsh , I Welters , R Welton , V Wenn , L Wentworth , J Wesonga , K Wesseldine , J West , M West , R West , S West , L Western , R Westhead , H Weston , A Westwood , K Westwood , S Westwood , B Wetherill , S Wheaver , H Wheeler , B Whelan , M Whelband , A Whileman , A Whitcher , A White , B White , C White , D White , J White , K White , M White , N White , S White , T White , C Whitehead , K Whitehorn , C Whitehouse , T Whitehouse , J Whiteley , L Whiteley , S Whiteley , R Whitham , G Whitlingum , D Whitmore , L Whittam , A Whittington , H Whittle , R Whittle , E Wiafe , L Wiblin , O Wickens , J Widdrington , J Wieboldt , H Wieringa , C Wiesender , L Wiffen , A Wight , A Wignall , C Wignall , A Wilce , D Wilcock , E Wilcock , L Wilcox , B Wild , L Wild , S Wild , M Wilde , L Wilding , P Wilding , T Wildsmith , J Wileman , K Wiles , E Wilhelmsen , T Wiliams , J Wilkie , D Wilkin , H Wilkins , J Wilkins , S Wilkins , I Wilkinson , L Wilkinson , N Wilkinson , S Wilkinson , T Wilkinson , S Willetts , A Williams , C Williams , D Williams , E Williams , G Williams , H Williams , J Williams , K Williams , M Williams , P Williams , R Williams , S Williams , T Williams , A Williamson , C Williamson , H Williamson , J Williamson , R Williamson , E Willis , H Willis , J Willis , L Wills , L Willsher , C Willshire , A Wilson , B Wilson , D Wilson , F Willson , I Wilson , J Willson , K Wilson , K-A Wilson , L Wilson , M Wilson , T Wilson , K Win , M Win , T Win , W Win , L Winckworth , L Winder , P Winder , S Winearl , H Winmill , S Winn , C Winpenny , H Winslow , H Winter , J Winter , B Winter-Goodwin , J Winterton , H Winwood , J Wischhusen , S Wisdom , M Wise , M Wiselka , R Wiseman , S Wiseman , S Wishart , T Wishlade , E Witele , N Withers , D Wixted , T Wodehouse , W Wolf , N Wolff , K Wolffsohn , R Wolf-Roberts , E Wolodimeroff , A Wolstencroft , A Wong , C Wong , C H Wong , E Wong , J Wong , K Wong , M Wong , N Wong , S Wong , T Wong , A Wood , D Wood , F Wood , G Wood , H Wood , J Wood , L Wood , M Wood , S Wood , T Wood , K Woodall , R Woodfield , C Woodford , E Woodford , J Woodford , L Woodhead , T Woodhead , P Woodland , M Woodman , S Woodmansey , C Woods , J Woods , K Woods , S Woods , Z Woodward , M Woolcock , G Wooldridge , R Woolf , C Woollard , L Woollen , E Woolley , J Woolley , D Woosey , D Wootton , J Wootton , D Worley , S Worton , J Wraight , M Wray , K Wren , L Wren , C Wrey Brown , C Wright , D Wright , F Wright , H Wright , I Wright , L Wright , R Wright , S Wright , T Wright , C Wroe , H Wroe , H Wu , P Wu , J Wubetu , R Wulandari , S Wurie , C Wyatt , F Wyn-Griffiths , I Wynter , B Xavier , A Xhikola , B Xia , Z Xia , T Y Ellis , E Yacoba , M Yakubi , M Yan , Y Yanagisawa , F Yang , Y Yang , M Yanney , W Yap , N Yaqoob , S Yasmin , B Yates , D Yates , E Yates , H Yates , M Yates , T Yates , J Ye , C Yearwood Martin , K Yein , F Yelnoorkar , A Yeoh , C Yeung , P Yew , D Yewatkar , L Ylquimiche Melly , I Ynter , H Yong , J Yorke , J Youens , A Younes Ibrahim , E Young , G Young , L Young , A Yousafzar , S Youssouf , A Yousuf , C Yu , J Yuan , B Yung , D Yusef , S Yusef , I Yusuf , A-M Zafar , S Zagalo , S Zaher , A Zahoor , M Zainab , T Zak , K Zaki , N Zakir , K Zalewska , A Zamalloa , M Zaman , S Zaman , J Zamikula , L Zammit , M Zammit-Mangion , M Zawadzka , E Zebracki , D Zehnder , L Zeidan , D Zeinali , J Zhang , X Zhao , D Zheng , M Zia , O Zibdeh , R Zill-E-Huma , E Zin , E Zincone , G Zindoga , E Zinkin , V Zinyemba , C Zipitis , L Zitter , A Zmierczak , G Zubikarai , A Zubir , N Zuhra , R Zulaikha , S Zulfikar , C Zullo , A Zuriaga-Alvaro

Background

Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS), also known as multisystem inflammatory syndrome in children (MIS-C) emerged in April, 2020. The paediatric comparisons within the RECOVERY trial aimed to assess the effect of intravenous immunoglobulin or corticosteroids compared with usual care on duration of hospital stay for children with PIMS-TS and to compare tocilizumab (anti-IL-6 receptor monoclonal antibody) or anakinra (anti-IL-1 receptor antagonist) with usual care for those with inflammation refractory to initial treatment.

Methods

We did this randomised, controlled, open-label, platform trial in 51 hospitals in the UK. Eligible patients were younger than 18 years and had been admitted to hospital for PIMS-TS. In the first randomisation, patients were randomly assigned (1:1:1) to usual care (no additional treatments), usual care plus methylprednisolone (10mg/kg per day for 3 consecutive days), or usual care plus intravenous immunoglobulin (a single dose of 2 g/kg). If further anti-inflammatory treatment was considered necessary, children aged at least 1 year could be considered for a second randomisation, in which patients were randomly assigned (1:2:2) to usual care, intravenous tocilizumab (12 mg/kg in patients <30 kg; 8mg/kg in patients ≥30 kg, up to a maximum dose of 800 mg), or subcutaneous anakinra (2 mg/kg once per day in patients ≥10 kg). Randomisation was by use of a web-based simple (unstratified) randomisation with allocation concealment. The primary outcome was duration of hospital stay. Analysis was by intention to treat. For treatments assessed in each randomisation, a single Bayesian framework assuming uninformative priors for treatment was used to jointly assess the efficacy of each intervention compared with usual care. The trial was registered with ISRCTN (50189673) and ClinicalTrials.gov (NCT04381936).

Findings

Between May 18, 2020, and Jan 20, 2022, 237 children with PIMS-TS were enrolled and included in the intention-to-treat analysis. Of the 214 patients who entered the first randomisation, 73 were assigned to receive intravenous immunoglobulin, 61 methylprednisolone, and 80 usual care. Of the 70 children who entered the second randomisation (including 23 who did not enter the first randomisation), 28 were assigned to receive tocilizumab, 14 anakinra, and 28 usual care. Mean age was 9·5 years (SD 3·8) in the randomisation and 9·6 years (3·6) in the second randomisation. 118 (55%) of 214 patients in the first randomisation and 39 (56%) of 70 patients in the second randomisation were male. 130 (55%) of 237 patients were Black, Asian, or minority ethnic, and 105 (44%) were White. Mean duration of hospital stay was 7·4 days (SD 0·4) in children assigned to intravenous immunoglobulin and 7·6 days (0·4) in children assigned to usual care (difference –0·1 days, 95% credible interval [CrI] –1·3 to 1·0; posterior probability 59%). Mean duration of hospital stay was 6·9 days (SD 0·5) in children assigned to methylprednisolone (difference from usual care –0·7 days, 95% CrI –1·9 to 0·6; posterior probability 87%). Mean duration of hospital stay was 6·6 days (SD 0·7) in children assigned to second-line tocilizumab and 9·9 days (0·9) in children assigned to usual care (difference –3·3 days, 95% CrI –5·6 to –1·0; posterior probability >99%). Mean duration of hospital stay was 8·5 days (SD 1·2) in children assigned to anakinra (difference from usual care –1·4 days, 95% CrI –4·3 to 1·8; posterior probability 84%). Two persistent coronary artery aneurysms were reported among patients assigned to usual care in the first randomisation. There were few cardiac arrythmias, bleeding, or thrombotic events in any group. Two children died; neither was considered related to study treatment.

Interpretation

Moderate evidence suggests that, compared with usual care, first-line intravenous methylprednisolone reduces duration of hospital stay for children with PIMS-TS. Good evidence suggests that second-line tocilizumab reduces duration of hospital stay for children with inflammation refractory to initial treatment. Neither intravenous immunoglobulin nor anakinra had any effect on duration of hospital stay compared with usual care.

Funding

Medical Research Council and National Institute of Health Research.

中文翻译：

与 SARS-CoV-2 暂时相关的儿科炎症多系统综合征儿童的免疫调节治疗（PIMS-TS、MIS-C；RECOVERY）：一项随机、对照、开放标签平台试验

背景

与 SARS-CoV-2 暂时相关的儿科多系统炎症综合征 (PIMS-TS)，也称为儿童多系统炎症综合征 (MIS-C) 于 2020 年 4 月出现。RECOVERY 试验中的儿科比较旨在评估静脉注射免疫球蛋白或皮质类固醇与常规治疗对 PIMS-TS 儿童住院时间的影响，以及对托珠单抗（抗 IL-6 受体单克隆抗体）或阿那白滞素（抗 IL-1 受体拮抗剂）与常规治疗的比较初始治疗难治的炎症。

方法

我们在英国 51 家医院进行了这项随机、对照、开放标签的平台试验。符合条件的患者年龄小于 18 岁，并且因 PIMS-TS 入院。在第一次随机分组中，患者被随机分配（1:1:1）至常规护理（无额外治疗）、常规护理加甲泼尼龙（每天 10mg/kg，连续 3 天）或常规护理加静脉注射免疫球蛋白（单次注射）。剂量为2克/公斤）。如果认为有必要进一步抗炎治疗，则可以考虑对至少 1 岁的儿童进行第二次随机分组，其中患者被随机分配（1:2:2）接受常规护理、静脉注射托珠单抗（患者为 12 mg/kg） <30公斤；≥30公斤的患者为8毫克/公斤，最大剂量为800毫克），或皮下注射阿那白滞素（≥10公斤的患者为2毫克/公斤，每天一次）。随机化是通过使用基于网络的简单（非分层）随机化和分配隐藏来实现的。主要结局是住院时间。分析是按意向治疗进行的。对于每次随机分组中评估的治疗，使用假设治疗先验信息不丰富的单一贝叶斯框架来联合评估每种干预措施与常规护理相比的疗效。该试验已在 ISRCTN (50189673) 和ClinicalTrials.gov ( NCT04381936 )注册。

发现

2020年5月18日至2022年1月20日期间，237名PIMS-TS儿童被纳入并纳入意向治疗分析。在进入第一次随机分组的 214 名患者中，73 名被分配接受静脉注射免疫球蛋白，61 名接受甲泼尼龙治疗，80 名接受常规护理。在进入第二次随机分组的 70 名儿童中（包括 23 名未进入第一次随机分组的儿童），28 名被分配接受托珠单抗治疗，14 名接受阿那白滞素治疗，28 名接受常规护理。随机分组中的平均年龄为 9·5 岁 (SD 3·8)，第二次随机分组中的平均年龄为 9·6 岁 (3·6)。第一次随机分组的 214 名患者中有 118 名患者（55%）是男性，第二次随机分组的 70 名患者中有 39 名患者（56%）为男性。237 名患者中有 130 名（55%）是黑人、亚洲人或少数民族，105 名（44%）是白人。接受静脉注射免疫球蛋白治疗的儿童的平均住院时间为 7·4 天 (SD 0·4)，接受常规护理的儿童的平均住院时间为 7·6 天 (0·4)（差异 –0·1 天，95% 可信区间） [CrI] –1·3 至 1·0；后验概率 59%）。接受甲基泼尼松龙治疗的儿童的平均住院时间为 6·9 天 (SD 0·5)（与常规护理的差异为 –0·7 天，95% CrI –1·9 至 0·6；后验概率 87%）。分配至二线托珠单抗的儿童的平均住院时间为 6·6 天 (SD 0·7)，分配至常规护理的儿童的平均住院时间为 9·9 天 (0·9)（差异 –3·3 天，95%） CrI –5·6 至 –1·0；后验概率 >99%）。分配至阿那白滞素组的儿童的平均住院时间为 8·5 天 (SD 1·2)（与常规护理不同 –1·4 天，95% CrI –4·3 至 1·8；后验概率 84%）。在第一次随机分组中分配到常规护理的患者中报告了两个持续性冠状动脉瘤。任何组中都很少出现心律失常、出血或血栓事件。两个孩子死了；两者均不被认为与研究治疗相关。