Systemic lupus erythematosus (SLE) disproportionately affects women during childbearing years, and hydroxychloroquine (HCQ) is the standard first-line treatment. Preeclampsia complicates up to one-third of pregnancies in lupus patients, although reports vary by parity and multifetal gestation. We investigated whether taking HCQ early in pregnancy may reduce the risk of preeclampsia.

中文翻译：

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羟氯喹在狼疮妊娠和先兆子痫风险中的作用


系统性红斑狼疮 (SLE) 对育龄妇女的影响尤为严重，羟氯喹 (HCQ) 是标准的一线治疗方法。尽管报告因胎次和多胎妊娠而异，但先兆子痫会使多达三分之一的狼疮患者妊娠变得复杂。我们调查了怀孕早期服用 HCQ 是否可以降低先兆子痫的风险。