Accurate glomerular filtration rate (GFR) assessment is essential in critically ill patients. GFR is often estimated using creatinine-based equations, which require surrogates for muscle mass such as age and sex. Race has also been included in GFR equations, based on the assumption that Black individuals have genetically determined higher muscle mass. However, race-based GFR estimation has been questioned with the recognition that race is a poor surrogate for genetic ancestry, and racial health disparities are driven largely by socioeconomic factors. The American Society of Nephrology and the National Kidney Foundation (ASN/NKF) recommend widespread adoption of new "race-free" creatinine equations, and increased use of cystatin C as a race-agnostic GFR biomarker.

中文翻译：

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在重症监护实践中实现公平的肾功能估计。重症监护医学会肾脏临床实践工作组的多样性、公平性和包容性指南。

准确的肾小球滤过率（GFR）评估对于危重患者至关重要。GFR 通常使用基于肌酐的方程进行估算，该方程需要肌肉质量的替代变量，例如年龄和性别。基于黑人基因决定较高肌肉质量的假设，种族也被纳入 GFR 方程中。然而，基于种族的 GFR 估计受到了质疑，因为人们认识到种族不能很好地替代遗传血统，而且种族健康差异主要是由社会经济因素驱动的。美国肾脏病学会和国家肾脏基金会 (ASN/NKF) 建议广泛采用新的“无种族”肌酐方程，并增加使用半胱氨酸蛋白酶抑制剂 C 作为与种族无关的 GFR 生物标志物。