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Hyperuricemia Subtypes Classified According to Renal Uric Acid Handling Manifesting Distinct Phenotypic and Genetic Profiles in People With Gout
Arthritis & Rheumatology ( IF 13.3 ) Pub Date : 2024-02-27 , DOI: 10.1002/art.42838
Han Qi 1, 2, 3, 4 , Mingshu Sun 5 , Robert Terkeltaub 6 , Tony R. Merriman 3, 7 , Haibing Chen 8 , Zhiqiang Li 2 , Aichang Ji 2 , Xiaomei Xue 1, 2, 3, 4 , Wenyan Sun 2 , Can Wang 2 , Xinde Li 2 , Yuwei He 2 , Lingling Cui 2 , Nicola Dalbeth 9 , Changgui Li 1, 2, 3, 4
Affiliation  

Hyperuricemia can be stratified into four subtypes according to renal uric acid handling. The aim of this study was to comprehensively describe the biologic characteristics (including genetic background) of clinically defined hyperuricemia subtypes in two large geographically independent gout cohorts.

中文翻译:

根据肾尿酸处理分类的高尿酸血症亚型在痛风患者中表现出不同的表型和遗传特征

根据肾脏尿酸处理,高尿酸血症可分为四种亚型。本研究的目的是全面描述两个地理独立的痛风队列中临床定义的高尿酸血症亚型的生物学特征(包括遗传背景)。
更新日期:2024-02-27
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