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Prevalence of postprandial hypotension in older adults: a systematic review and meta-analysis
Age and Ageing ( IF 6.7 ) Pub Date : 2024-02-27 , DOI: 10.1093/ageing/afae022
Lei Huang 1 , Sheyu Li 2, 3 , Xiaofeng Xie 1 , Xiaoli Huang 4, 5 , Lily Dongxia Xiao 6 , Ying Zou 1 , Wenyi Jiang 1 , Fengying Zhang 1
Affiliation  

Background Older adults with postprandial hypotension (PPH) increase susceptibility to falls, syncope, stroke, acute cardiovascular diseases and even death. However, the prevalence of this condition varies significantly across studies. We aimed to determine the prevalence of PPH in older adults. Methods Web of Science, PubMed, Cochrane Library, Embase and CINAHL were searched from their inception until February 2023. Search terms included ‘postprandial period’, ‘hypotension’ and ‘postprandial hypotension’. Eligible studies were assessed using the Joanna Briggs Institute tool. Meta-analyses were performed among similar selected studies. Results Thirteen eligible studies were included, and data from 3,021 participants were pooled. The meta-analysis revealed a PPH prevalence of 40.5% [95% confidence interval (CI): 0.290–0.519] in older adults, and this was prevalent in the community (32.8%, 95% CI: 0.078–0.647, n = 1,594), long-term healthcare facility (39.4%, 95% CI: 0.254–0.610, n = 1,062) and geriatrics department of hospitals (49.3%, 95% CI: 0.357–0.630, n = 365). The pooled results showed significant heterogeneity (I2 > 90%), partially related to the different ages, sex, pre-prandial systolic blood pressure levels of participants, or the different criteria and methodology used to diagnose PPH. Conclusions PPH is a prevalent condition in older adults. Further research is needed to confirm this result, and priority should be given to establishing international consensus on PPH diagnostic criteria and designing its diagnostic procedure.

中文翻译:

老年人餐后低血压的患病率:系统评价和荟萃分析

背景 患有餐后低血压(PPH)的老年人会增加跌倒、晕厥、中风、急性心血管疾病甚至死亡的风险。然而,不同研究中这种情况的患病率差异很大。我们的目的是确定老年人中 PPH 的患病率。方法 Web of Science、PubMed、Cochrane Library、Embase 和 CINAHL 的搜索范围从建库到 2023 年 2 月。搜索术语包括“餐后时期”、“低血压”和“餐后低血压”。使用乔安娜布里格斯研究所工具评估合格的研究。在相似的选定研究中进行荟萃分析。结果 纳入了 13 项符合条件的研究,汇集了 3,021 名参与者的数据。荟萃分析显示,老年人中 PPH 患病率为 40.5% [95% 置信区间 (CI):0.290–0.519],这在社区中很普​​遍(32.8%,95% CI:0.078–0.647,n = 1,594 )、长期医疗机构(39.4%,95% CI:0.254–0.610,n = 1,062)和医院老年科(49.3%,95% CI:0.357–0.630,n = 365)。汇总结果显示出显着的异质性(I2>90%),部分与参与者的不同年龄、性别、餐前收缩压水平或用于诊断PPH的不同标准和方法有关。结论 PPH 是老年人中的一种常见疾病。这一结果仍需进一步研究证实,并应优先建立国际共识的 PPH 诊断标准并设计其诊断程序。
更新日期:2024-02-27
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