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Controlling brown adipose tissue size through EPAC1
Nature Reviews Endocrinology ( IF 40.5 ) Pub Date : 2024-03-04 , DOI: 10.1038/s41574-024-00971-3
Francesc Villarroya , Marta Giralt

A new study by Reverte-Salisa and colleagues identifies a molecular mechanism through which the cAMP-mediating protein EPAC1 controls the size of brown and beige adipose tissue. This finding opens the door for the development of pharmacological interventions to prevent the decline of brown adipose tissue in obesity and ageing, and thereby improve metabolic health.

中文翻译:

通过 EPAC1 控制棕色脂肪组织的大小

Reverte-Salisa 及其同事的一项新研究确定了 cAMP 介导蛋白 EPAC1 控制棕色和米色脂肪组织大小的分子机制。这一发现为开发药物干预措施打开了大门,以防止肥胖和衰老过程中棕色脂肪组织的减少,从而改善代谢健康。
更新日期:2024-03-04
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