Haemodialyser technology has not advanced much in decades, despite its unresolved shortcomings. Sophisticated new computational tools such as high-fidelity surrogate in silico dialyser models could reduce the time and expense of exploring alternative designs, dialysis dose and operating conditions compared with the current gold standard in vitro studies.

中文翻译：

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通过中空纤维血液透析器的计算建模创新透析

尽管存在尚未解决的缺点，血液透析器技术几十年来并没有取得太大进展。与当前的金标准体外研究相比，先进的新计算工具（例如高保真替代硅透析器模型）可以减少探索替代设计、透析剂量和操作条件的时间和费用。