To evaluate the outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) under different levels of glaucoma severity. Retrospective, multicenter, before-and-after study. One eye from all primary open-angle glaucoma patients who underwent GATT combined with cataract surgery (Phaco-GATT) or GATT stand-alone with 12 months of follow-up were included and divided according to glaucoma severity (mild = GI, moderate = GII, and advanced = GIII) and the outcomes compared. A total of 270 eyes were included: 90 in GI, 75 in GII, and 105 in GIII. The IOP was reduced from 18.6 ± 6.0 mm Hg in GI, 19.7 ± 6.4 mm Hg in GII, and 21.0 ± 7.9 mm Hg in GIII, preoperatively, to 11.9 ± 2.6 mm Hg in GI, 11.8 ± 2.1 mm Hg in GII, and 11.9 ± 3.0 mm Hg in GIII at 12 months postoperatively ( < .001 for all). The number of hypotensive ocular medications were reduced from 2.7 ± 1.0 in GI, 3.1 ± 0.8 in GII, and 3.2 ± 1.2 in GIII to 0.6 ± 0.9 in GI, 1.0 ± 1.1 in GII, and 1.2 ± 1.1 in GIII at the last postoperative visit ( < .001 for all). Relative success was achieved, at 1 year, in 93.8% of the eyes in GI, 89.0% in GII, and 88.1% in GIII ( = .3). Complete success was achieved in 61.8% of the eyes in GI, 43.8% in GII, and 37.6% in GIII ( = .007). No serious adverse event was observed in any group. GATT is a safe and effective procedure in glaucoma, regardless of its preoperative severity.

中文翻译：

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不同青光眼严重程度下房角镜辅助经腔小梁切开术的结果：一项多中心比较研究

评估不同青光眼严重程度下房角镜辅助腔内小梁切开术 (GATT) 的结果。回顾性、多中心、前后研究。纳入所有接受 GATT 联合白内障手术 (Phaco-GATT) 或单独 GATT 并随访 12 个月的原发性开角型青光眼患者的一只眼睛，并根据青光眼严重程度进行分类（轻度 = GI，中度 = GII） ，和高级= GIII）和结果进行比较。总共纳入 270 只眼睛：GI 90 只、GII 75 只、GIII 105 只。术前眼压从 GI 的 18.6 ± 6.0 mm Hg、GII 的 19.7 ± 6.4 mm Hg 和 GIII 的 21.0 ± 7.9 mm Hg 降低至 GI 的 11.9 ± 2.6 mm Hg、GII 的 11.8 ± 2.1 mm Hg 和术后 12 个月时 GIII 为 11.9 ± 3.0 mm Hg（全部 < .001）。最后一次术后，降压眼科药物的数量从胃肠道 2.7 ± 1.0、GII 3.1 ± 0.8、GIII 3.2 ± 1.2 减少至 GI 0.6 ± 0.9、GII 1.0 ± 1.1、GIII 1.2 ± 1.1访问（所有 < .001）。 1 年时，93.8% 的 GI 眼睛、89.0% 的 GII 眼睛和 88.1% 的 GIII 眼睛获得了相对成功 (= .3)。 61.8% 的 GI 眼睛、43.8% 的 GII 眼睛和 37.6% 的 GIII 眼睛获得完全成功 (= .007)。任何组均未观察到严重不良事件。无论术前严重程度如何，GATT 都是治疗青光眼的一种安全有效的手术。