The number of heart transplants in the United States has continued to increase. Since 2011, pediatric heart transplants have increased 31.7% to 494 and adult heart transplants have increased 85.8% to 3,668 in 2022. The numbers of new candidates for pediatric and adult heart transplants have also increased, with 703 new pediatric candidates and 4,446 new adult candidates in 2022. Adult heart transplant rates continue to rise, peaking at 122.5 transplants per 100 patient-years in 2022; however, the pediatric heart transplant rate decreased to its lowest rate in the past decade, 104.2 transplants per 100 patient-years, a decrease of 13.9% from 121 transplants per 100 patient-years in 2011. Despite this, pretransplant mortality among pediatric candidates has decreased by 52.2%, from 20.8 deaths per 100 patient-years in 2011 to 10.0 deaths per 100 patient-years in 2022, but remains excessive for candidates younger than 1 year at 25.7 deaths per 100 patient-years. Among adult candidates, pretransplant mortality declined from 15 deaths per 100 patient-years in 2011 to 8.7 deaths per 100 patient-years in 2022. Since 2011, posttransplant mortality has been stable to slightly better; among recipients who underwent transplant in 2015-2017, the 1-, 3-, and 5-year pediatric survival rates were 93.7%, 89.2%, and 85.0%, respectively, and the adult survival rates were 91.3%, 85.7%, and 80.4%. Donor trends have been favorable, with an increase in the numbers of hearts recovered and growing numbers of hearts procured after circulatory death.

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OPTN/SRTR 2022年度数据报告：心脏

美国的心脏移植数量持续增加。自2011年以来，儿童心脏移植数量增加了31.7%，达到494例，成人心脏移植数量增加了85.8%，到2022年达到3,668例。儿童和成人心脏移植的新候选人数量也有所增加，新增儿科候选人703名，成人新候选人4,446名2022 年。成人心脏移植率继续上升，2022 年达到每 100 名患者年 122.5 例移植的峰值；然而，儿科心脏移植率下降至过去十年来的最低水平，为每 100 患者年 104.2 例，比 2011 年每 100 患者年 121 例下降了 13.9%。尽管如此，儿科候选者的移植前死亡率仍呈下降趋势。下降了 52.2%，从 2011 年每 100 患者年 20.8 例死亡下降到 2022 年每 100 患者年 10.0 例死亡，但对于 1 岁以下的候选人来说仍然过高，每 100 患者年 25.7 例死亡。在成年候选者中，移植前死亡率从 2011 年的每 100 患者年 15 例死亡下降到 2022 年的每 100 患者年 8.7 例死亡。自 2011 年以来，移植后死亡率一直稳定或略有改善； 2015-2017年接受移植的受者中，儿童1年、3年和5年生存率分别为93.7%、89.2%和85.0%，成人生存率分别为91.3%、85.7%和85.0%。 80.4%。捐赠者趋势一直良好，回收的心脏数量有所增加，循环死亡后获得的心脏数量也有所增加。