The field of alkene difunctionalization is undergoing vigorous advancement with a primary focus on two key aspects: the innovation of new reagents and the exploration of novel reaction sites. Recently in Nature, Maulide and co-workers reported a general and synthetically useful methodology for the stereodivergent 1,3- difunctionalization of unactivated alkenes via a charge-relocation pathway.

中文翻译：

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利用电荷重新定位：烯烃远程​​双官能化的一种新方法

烯烃双官能化领域正在蓬勃发展，主要集中在两个关键方面：新试剂的创新和新反应位点的探索。最近，Maulide 及其同事在《自然》杂志上报道了一种通用且综合有用的方法，用于通过电荷重定位途径对未活化的烯烃进行立体发散 1,3-双官能化。