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A Short Review on the Synthetic Routes for the Antiepileptic Drug (S)-Levetiracetam
Organic Process Research & Development ( IF 3.4 ) Pub Date : 2024-03-23 , DOI: 10.1021/acs.oprd.4c00002
Sayantan Paul 1, 2 , Asish K. Bhattacharya 1, 2
Affiliation  

Epilepsy is a chronic disorder characterized by recurrent unpredictable seizures. Levetiracetam (Keppra) was introduced by UCB for the treatment of partial onset seizures in patients above 16 years of age diagnosed with epilepsy. This review reports synthetic strategies available for the synthesis of (S)-levetiracetam and will certainly aid the quest for the development of new routes for its synthesis.

中文翻译:

抗癫痫药(S)-左乙拉西坦的合成路线简述

癫痫是一种慢性疾病,其特征是反复发作、不可预知的癫痫发作。左乙拉西坦 (Keppra) 由 UCB 推出,用于治疗 16 岁以上诊断为癫痫患者的部分性癫痫发作。这篇综述报告了可用于合成 ( S )-左乙拉西坦的合成策略,并且肯定有助于寻求其合成新路线的开发。
更新日期:2024-03-23
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