Hemoglobin A1c (A1C) is widely used for the diagnosis and management of diabetes. Accurate measurement of A1C is necessary for optimal clinical value. Assay standardization has markedly improved the accuracy and consistency of A1C testing. Devices to measure A1C at point of care (POC) are commercially available, allowing rapid results when the patient is seen. In this review, we describe how standardization of A1C testing was achieved, leading to high-quality results in clinical laboratories. We address the use of POC A1C testing in clinical situations and summarize the advantages and disadvantages of POC A1C testing. We emphasize the importance of considering the limitations of these devices and following correct testing procedures to ensure that accurate A1C results are obtained for optimal care of patients.

中文翻译：

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临床实践中的护理点 HbA1c：最佳使用的注意事项和注意事项

糖化血红蛋白 (A1C) 广泛用于糖尿病的诊断和治疗。准确测量 A1C 对于获得最佳临床价值是必要的。检测标准化显着提高了 A1C 检测的准确性和一致性。用于在护理点 (POC) 测量 A1C 的设备已经上市，可以在患者就诊时快速获得结果。在这篇综述中，我们描述了如何实现 A1C 测试的标准化，从而在临床实验室中获得高质量的结果。我们讨论了 POC A1C 测试在临床情况下的使用，并总结了 POC A1C 测试的优点和缺点。我们强调考虑这些设备的局限性并遵循正确的测试程序的重要性，以确保获得准确的 A1C 结果，从而为患者提供最佳护理。