Chemical reactions can be promoted at lower temperatures and pressures, thereby reducing the energy input, by introducing suitable catalysts. Despite its significance, the quest for efficient and stable catalysts remains a significant challenge. In this context, addressing the efficiency of catalysts stands out as a paramount concern. However, the challenges posed by the vague structure and limited tailorability of traditional catalysts would make it highly desirable to fabricate optimized catalysts based on the understanding of structure–activity relationships. Covalent organic frameworks (COFs), a subclass of fully designed crystalline materials formed by the polymerization of organic building blocks through covalent bonds have garnered widespread attention in catalysis. The precise and customizable structures of COFs, coupled with attributes such as high surface area and facile functional modification, make COFs attractive molecular platforms for catalytic applications. These inherent advantages position COFs as ideal catalysts, facilitating the elucidation of structure-performance relationships and thereby further improving the catalysis. Nevertheless, there is a lack of systematic emphasis on and summary of structural regulation at the atomic/molecular level for COF catalysis. Consequently, there is a growing need to summarize this research field and provide deep insights into COF-based catalysis to promote its further development.

中文翻译：

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催化共价有机框架的结构调控

通过引入合适的催化剂，可以在较低的温度和压力下促进化学反应，从而减少能量输入。尽管具有重要意义，但寻找高效稳定的催化剂仍然是一个重大挑战。在这种背景下，解决催化剂的效率问题就成为最重要的问题。然而，传统催化剂的模糊结构和有限的可定制性带来的挑战使得非常需要基于对结构-活性关系的理解来制造优化的催化剂。共价有机框架（COF）是完全设计的晶体材料的一个子类，由有机结构单元通过共价键聚合形成，在催化领域引起了广泛的关注。 COF 的精确且可定制的结构，加上高表面积和易于功能修饰等属性，使 COF 成为催化应用中有吸引力的分子平台。这些固有的优势使 COF 成为理想的催化剂，有助于阐明结构-性能关系，从而进一步改善催化作用。然而，目前对COF催化在原子/分子水平上的结构调控缺乏系统的重视和总结。因此，越来越需要总结这一研究领域并为COF基催化提供深入的见解，以促进其进一步发展。