A cross-sectional multinational collaborative study on women with endometriosis from Latin America and Spain uncovered high levels of painful symptomatology and high pain catastrophizing scores. Associations between pain perception/catastrophizing and race/ethnicity have been documented. This study was conducted to uncover factors moderating pelvic pain severity, including socioeconomic variables, self-identified race, and pain catastrophizing in women with endometriosis from Latin America and Spain, a population encompassing diverse racial and sociocultural contexts. Self-reported data on demographics, clinical history, Ob-Gyn history, pelvic pain intensity, and pain catastrophizing were collected with the Spanish World Endometriosis Research Foundation (WERF) Endometriosis Phenome Project (EPhect) Clinical Questionnaire (ECQ). Multiple logistic regression was conducted to analyze effects of self-identified race, demographic clusters (defined as countries with similar racial population distribution), socioeconomic factors, and pain catastrophizing on reporting severe vs moderate-mild levels of dysmenorrhea, dyspareunia, and pelvic pain. Self-identified race did not affect the likelihood of reporting severe pelvic pain; however, there were significant differences in reporting severe dysmenorrhea at worst among demographic clusters. Older age was associated with severe dyspareunia at worst and recent pelvic pain. Pain catastrophizing score was highly predictive of reporting most types of severe pelvic pain, regardless of race and demographic cluster. These results negate a role of racial categories as moderator of pain in women from Latin America and Spain and support integration of pain catastrophizing assessments and psychological interventions into the pain management plan to enhance therapeutic outcomes and QoL for patients with endometriosis.

中文翻译：

---

揭示拉丁美洲和西班牙子宫内膜异位症女性疼痛感知的调节因素：社会人口统计学、种族自我认同和疼痛灾难化的作用。

一项针对拉丁美洲和西班牙患有子宫内膜异位症的女性进行的横断面跨国合作研究发现，她们有高水平的疼痛症状和高疼痛灾难性评分。疼痛感知/灾难化与种族/民族之间的关联已被记录。这项研究的目的是揭示缓解盆腔疼痛严重程度的因素，包括社会经济变量、自我认同的种族，以及拉丁美洲和西班牙子宫内膜异位症女性的疼痛灾难性症状，这些女性来自不同的种族和社会文化背景。通过西班牙世界子宫内膜异位症研究基金会 (WERF) 子宫内膜异位症表型项目 (EPhect) 临床问卷 (ECQ) 收集有关人口统计、临床病史、妇产科病史、盆腔疼痛强度和疼痛灾难化的自我报告数据。采用多元逻辑回归分析自我认同种族、人口群体（定义为具有相似种族人口分布的国家）、社会经济因素和疼痛灾难化对报告重度与中轻度痛经、性交疼痛和盆腔疼痛的影响。自我认同的种族并不影响报告严重骨盆疼痛的可能性；然而，不同人群报告的最严重痛经情况存在显着差异。年龄较大与严重的性交困难（最严重的情况）和最近的骨盆疼痛有关。疼痛灾难化评分可以高度预测大多数类型的严重骨盆疼痛，无论种族和人口群体如何。这些结果否定了种族类别作为拉丁美洲和西班牙女性疼痛调节因素的作用，并支持将疼痛灾难性评估和心理干预纳入疼痛管理计划，以提高子宫内膜异位症患者的治疗结果和生活质量。