In the first comprehensive mRNA isoform atlas of the developing and adult mouse brain, we discover that region and age influence the isoform repertoire of cell subtypes. We link peak cell type regulation to the critical development period and report attenuated levels in adulthood.

中文翻译：

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发育中和成年小鼠大脑中选择性剪接的广泛变化

在发育中和成年小鼠大脑的第一个综合 mRNA 同工型图谱中，我们发现区域和年龄影响细胞亚型的同工型库。我们将细胞类型调节峰值与关键发育期联系起来，并报告了成年期的减弱水平。