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EphB2 Receptor Promotes Dermal Fibrosis in Systemic Sclerosis
Arthritis & Rheumatology ( IF 13.3 ) Pub Date : 2024-04-08 , DOI: 10.1002/art.42858
Erika SA Egal 1 , Severin Donald Kamdem 1 , Masaaki Yoshigi 1 , Ching‐Chu Yang 1 , Sarah Pellizzari 1 , Ernest M Kameni 1 , My N Helms 2 , Shervin Assassi 3 , Mark Henkemeyer 4 , Tracy M Frech 5 , Patrice N Mimche 1
Affiliation  

Erythropoietin-producing hepatocellular (Eph)/Ephrin cell–cell signaling is emerging as a key player in tissue fibrogenesis. The aim of this study was to test the hypothesis that the receptor tyrosine kinase EphB2 mediates dermal fibrosis in systemic sclerosis (SSc).

中文翻译:

EphB2 受体促进系统性硬化症中的真皮纤维化

产生促红细胞生成素的肝细胞 (Eph)/Ephrin 细胞间信号传导正在成为组织纤维形成的关键参与者。本研究的目的是检验受体酪氨酸激酶 EphB2 介导系统性硬化症 (SSc) 中真皮纤维化的假设。
更新日期:2024-04-08
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