当前位置: X-MOL 学术Nat. Metab. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
NCOR1/2 and glucocorticoid receptor orchestrate hepatic function
Nature Metabolism ( IF 20.8 ) Pub Date : 2024-04-15 , DOI: 10.1038/s42255-024-01028-5
Chloé Van Leene , Karolien De Bosscher

In this issue of Nature Metabolism, the research team of Mitchell Lazar reveals unexpected consequences of double loss of the coregulators NCOR1 and NCOR2 (NCOR1/2) in hepatocytes of adult mice, which affects chromatin functioning and glucocorticoid receptor (GR)-mediated gene transcription.

中文翻译:

NCOR1/2 和糖皮质激素受体协调肝功能

在本期《Nature Metabolism》中,Mitchell Lazar 的研究团队揭示了成年小鼠肝细胞中核心调节因子 NCOR1 和 NCOR2 (NCOR1/2) 双重丢失的意外后果,这会影响染色质功能和糖皮质激素受体 (GR) 介导的基因转录。
更新日期:2024-04-15
down
wechat
bug