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ASDAS-CRP and ASDAS-ESR cut-offs for disease activity states in axial spondyloarthritis - Are they interchangeable?
The Journal of Rheumatology ( IF 3.9 ) Pub Date : 2024-04-15 , DOI: 10.3899/jrheum.2023-1217
Stylianos Georgiadis , Lykke Midtbøll Ørnbjerg , Brigitte Michelsen , Tore K. Kvien , Daniela Di Giuseppe , Johan K. Wallman , Jakub Závada , Sella A. Provan , Eirik Klami Kristianslund , Ana Maria Rodrigues , Maria José Santos , Žiga Rotar , Katja Perdan Pirkmajer , Dan Nordström , Gary J. Macfarlane , Gareth T. Jones , Irene van der Horst-Bruinsma , Pasoon Hellamand , Mikkel Østergaard , Merete Lund Hetland

Ankylosing Spondylitis Disease Activity Score with C-reactive protein (ASDAS-CRP) is recommended over erythrocyte sedimentation rate (ASDAS-ESR) to assess disease activity in axial spondyloarthritis (axSpA). Although ASDAS-CRP and ASDAS-ESR are not interchangeable, the same disease activity cut-offs are used for both. We aimed to estimate optimal ASDAS-ESR values corresponding to the established ASDAS-CRP cut-offs (1.3, 2.1 and 3.5) and investigate the potential improvement of level of agreement between ASDAS-ESR and ASDAS-CRP disease activity states when applying these estimated cut-offs.

中文翻译:

中轴型脊柱关节炎疾病活动状态的 ASDAS-CRP 和 ASDAS-ESR 截止值 - 它们可以互换吗?

建议使用 C 反应蛋白强直性脊柱炎疾病活动评分 (ASDAS-CRP) 优于红细胞沉降率 (ASDAS-ESR) 来评估中轴型脊柱关节炎 (axSpA) 的疾病活动。尽管 ASDAS-CRP 和 ASDAS-ESR 不可互换,但两者使用相同的疾病活动截止值。我们的目的是估计与已建立的 ASDAS-CRP 临界值(1.3、2.1 和 3.5)相对应的最佳 ASDAS-ESR 值,并研究应用这些估计值时 ASDAS-ESR 和 ASDAS-CRP 疾病活动状态之间的一致性水平的潜在改进截止。
更新日期:2024-04-15
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