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Peripheral HMGB1 is linked to O3 pathology of disease-associated astrocytes and amyloid
Alzheimer's & Dementia ( IF 14.0 ) Pub Date : 2024-04-16 , DOI: 10.1002/alz.13825
Chandrama Ahmed 1 , Hendrik J. Greve 1 , Carla Garza‐Lombo 1 , Jamie A. Malley 1 , James A. Johnson 1 , Adrian L. Oblak 2 , Michelle L. Block 1
Affiliation  

Ozone (O3) is an air pollutant associated with Alzheimer's disease (AD) risk. The lung–brain axis is implicated in O3-associated glial and amyloid pathobiology; however, the role of disease-associated astrocytes (DAAs) in this process remains unknown.

中文翻译:

外周 HMGB1 与疾病相关星形胶质细胞和淀粉样蛋白的 O3 病理有关

臭氧 (O 3 ) 是一种与阿尔茨海默病 (AD) 风险相关的空气污染物。肺-脑轴与 O 3相关的神经胶质和淀粉样蛋白病理学有关;然而,疾病相关星形胶质细胞(DAA)在此过程中的作用仍不清楚。
更新日期:2024-04-16
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