Owing to the nonavailability of any clear targets for molluscicides against Pomacea canaliculata, target-based screening strategy cannot be employed. In this study, the molluscicidal effects of typical pesticides on P. canaliculata were evaluated to obtain the molluscicide target. A series of arylpyrrole compounds were synthesized based on the discovered target, and their structure–activity relationships explored. A preliminary strategy for screening molluscicides based on specific targets was also developed.

中文翻译：

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福寿螺杀软体动物新靶点筛选及鉴定

由于没有任何明确的针对福寿螺的杀软体动物靶点，因此无法采用基于靶点的筛选策略。本研究评价了典型农药对P. canaliculata的杀螺效果，以获得杀螺目标。基于发现的靶标合成了一系列芳基吡咯化合物，并探讨了它们的构效关系。还制定了基于特定目标筛选杀软体动物剂的初步策略。