Biofouling is the adherence of micro-organisms on submerged surfaces, which is a common phenomenon presenting a serious hazard to industry and public health. Nanozymes with haloperoxidase mimic activity are promising options to combat biofouling because HBrO generated by them can kill micro-organisms effectively. However, in haloperoxidase mimic nanozyme-involved antibiofouling, massive H₂O₂ injection is a requisite, which causes secondary pollution. To achieve self-sufficient H₂O₂ supply in antibiofouling, a wheel-like polyoxometalate (POM) compound, Ni₁₆Mo₁₆P₂₄, was synthesized. As an artificial nanozyme, Ni₁₆Mo₁₆P₂₄ shows excellent haloperoxidase mimic activity. In the electrocatalytic oxygen reduction reaction (ORR), it shows typical two-electron character and H₂O₂ production rate reaches 1394.5, 1245.5 and 1053 mM g⁻¹ h⁻¹ at 0.1, 0.3 and 0.5 V (vs. RHE) in neutral electrolyte. With H₂O₂ produced by electrocatalysis, Ni₁₆Mo₁₆P₂₄ accelerates the conversion from Br⁻ to HBrO and achieves “additional H₂O₂ free” antibiofouling. For bifunctional Ni₁₆Mo₁₆P₂₄, the structure–activity connection is clarified for haloperoxidase mimic activity and electrocatalytic H₂O₂ production property. More importantly, an environmentally friendly antibiofouling strategy is developed.

中文翻译：

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轮状多金属氧酸盐，用于卤过氧化物酶启发的电催化原位 H2O2 抗生物污染

生物污垢是微生物附着在水下表面上的现象，是对工业和公共健康构成严重危害的常见现象。具有卤过氧化物酶模拟活性的纳米酶是对抗生物污垢的有前途的选择，因为它们产生的 HBrO 可以有效杀死微生物。然而，在卤代过氧化物酶模拟纳米酶抗生物污损中，需要大量注入H ₂ O ₂ ，​​从而造成二次污染。为了实现抗生物污损中自给自足的H ₂ O ₂供应，合成了一种轮状多金属氧酸盐（POM）化合物Ni ₁₆ Mo ₁₆ P ₂₄ 。作为一种人工纳米酶，Ni ₁₆ Mo ₁₆ P ₂₄显示出优异的卤过氧化物酶模拟活性。在电催化氧还原反应（ORR）中，表现出典型的双电子特征，在0.1、0.3和0.5 V（相对于RHE）下， H ₂ O ₂产率分别达到1394.5、1245.5和1053 mM g ^-1 h ^{-1 。}中性电解质。Ni ₁₆ Mo ₁₆ P ₂₄利用电催化产生的H ₂ O _2加速Br ^-向HBrO的转化，实现“无额外H ₂ O ₂ ”的防污效果。对于双功能Ni ₁₆ Mo ₁₆ P ₂₄，阐明了卤过氧化物酶模拟活性和电催化H ₂ O ₂生产性能的结构-活性联系。更重要的是，开发了一种环境友好的抗生物污损策略。