A gold(I)-catalyzed protecting-group-free benzannulation approach to functionalized NH-carbazoles was accomplished via the hydroarylation of alkynes with 2-alkenylindoles. A broad spectrum of terminal and internal alkynes and 2-alkenylindoles successfully participated in this annulation reaction. The protocol efficiently enabled the formation of substituted NH-carbazoles with moderate to specific regioselectivities. The synthetic utility of this protocol was demonstrated by a variety of post-functionalizations.

中文翻译：

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金催化 2-烯基吲哚与炔的苯环化：一种无保护基的咔唑区域选择性方法

通过炔烃与 2-烯基吲哚的加氢芳基化，实现了金 ( I ) 催化的无保护基苯并环化方法来制备官能化 NH-咔唑。多种末端炔烃和内部炔烃以及 2-烯基吲哚成功地参与了该环化反应。该方案有效地形成了具有中等至特定区域选择性的取代 NH-咔唑。该协议的合成实用性通过各种后功能化得到了证明。