ObjectiveTo examine long‐term complications in women with stress urinary incontinence (SUI) and pelvic organ prolapse (POP), with and without surgical mesh implants.DesignLongitudinal open cohort study from 1 April 2006 (or 1 April 2012) to 30 November 2018.SettingThe Clinical Practice Research Datalink (CPRD) Gold database, which is linked to Hospital Episodes Statistics (HES) inpatient data, the HES Diagnostic Imaging Dataset (DID), Office for National Statistics mortality data and Index of Multiple Deprivation socio‐economic status data.SampleWomen aged ≥18 years with a diagnostic SUI/POP Read code.MethodsRates are estimated using negative binomial regression.Main outcome measuresRates of referrals for: psychological and pain services; urinalysis, C‐reactive protein (CRP) and erythrocyte sedimentation rate (ESR) testing; and pelvic ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI) scans.ResultsA cohort of 220 544 women were eligible for inclusion; 74% (n = 162 687) had SUI, 37% (n = 82 123) had POP and 11% (n = 24 266) had both. Rates of psychological referrals and CT scans were lower in women with SUI mesh surgery, but this was offset by higher rates of CRP testing in women with SUI or POP mesh, MRI scans in women with SUI mesh, and urinalysis testing and referrals to pain clinics for women with POP mesh.ConclusionsOur results suggest a higher burden of morbidity in women with SUI/POP mesh surgery, and that these women may require ongoing follow‐up in the primary care setting.

中文翻译：

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阴道手术网状装置对英国初级保健中疼痛诊所和心理服务转诊、抗炎测试和盆腔扫描的长期影响：临床实践研究数据链的队列研究

目的检查有或没有手术网状植入物的压力性尿失禁（SUI）和盆腔器官脱垂（POP）女性的长期并发症。设计2006年4月1日（或2012年4月1日）至2018年11月30日的纵向开放队列研究。临床实践研究数据链 (CPRD) 黄金数据库，与医院发作统计 (HES) 住院患者数据、HES 诊断影像数据集 (DID)、国家统计局死亡率数据和多重剥夺社会经济状况数据索引相关联。SampleWomen年龄≥18岁，具有诊断性SUI/POP阅读代码。方法使用负二项式回归估计比率。主要结果测量转介率：心理和疼痛服务；尿液分析、C反应蛋白（CRP）和红细胞沉降率（ESR）检测；结果 220 544 名女性符合纳入条件； 74%（n= 162 687) 有 SUI，37% (n= 82 123) 有 POP 且 11% (n= 24 266）两者都有。接受 SUI 网片手术的女性的心理转诊和 CT 扫描率较低，但这被接受 SUI 或 POP 网片手术的女性进行 CRP 检测、接受 SUI 网片女性进行 MRI 扫描、尿液分析检测和转诊至疼痛诊所的较高比率所抵消对于接受 POP 网片手术的女性。结论我们的结果表明，接受 SUI/POP 网片手术的女性发病率较高，这些女性可能需要在初级保健机构中进行持续随访。