The World Health Organization roadmap for neglected tropical diseases (NTDs) sets out ambitious targets for disease control and elimination by 2030, including 90% fewer people requiring interventions against NTDs and the elimination of at least 1 NTD in 100 countries. Mathematical models are an important tool for understanding NTD dynamics, optimizing interventions, assessing the efficacy of new tools, and estimating the economic costs associated with control programs. As NTD control shifts to increased country ownership and programs progress toward disease elimination, tailored models that better incorporate local context and can help to address questions that are important for decision-making at the national level are gaining importance. In this introduction to the supplement, New Tools and Nuanced Interventions to Accelerate Achievement of the 2030 Roadmap for Neglected Tropical Diseases, we discuss current challenges in generating more locally relevant models and summarize how the articles in this supplement present novel ways in which NTD modeling can help to accelerate achievement and sustainability of the 2030 targets.

中文翻译：

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新工具和细致入微的干预措施加速实现 2030 年被忽视热带病路线图

世界卫生组织针对被忽视的热带病 (NTD) 的路线图制定了到 2030 年控制和消除疾病的雄心勃勃的目标，包括将需要针对 NTD 进行干预的人数减少 90%，并在 100 个国家消除至少 1 种 NTD。数学模型是了解 NTD 动态、优化干预措施、评估新工具的功效以及估计与控制计划相关的经济成本的重要工具。随着被忽视的热带病控制转向国家自主权的增加以及消除疾病计划的进展，更好地融入当地情况并有助于解决对国家层面决策重要的问题的定制模型变得越来越重要。在增刊《加速实现 2030 年被忽视热带病路线图的新工具和细致干预措施》的介绍中，我们讨论了当前在生成更多本地相关模型方面面临的挑战，并总结了本增刊中的文章如何提出 NTD 建模的新方法。有助于加快实现 2030 年目标并实现其可持续性。