Potato virus Y (PVY) is a prominent representative of plant viruses. It can inflict severe damage upon Solanaceae plants, leading to global dissemination and substantial economic losses. To discover new antiviral agents, a class of planar chiral thiourea molecules through the key step of N-heterocyclic carbene-catalyzed nitrile formation reaction was synthesized with excellent optical purities for antiviral evaluations against plant virus PVY.

中文翻译：

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[2.2]对环芳烷平面手性硫脲衍生物的设计、合成及其抗PVY活性

马铃薯Y病毒（PVY）是植物病毒的突出代表。它会对茄科植物造成严重损害，导致全球传播和巨大的经济损失。为了发现新的抗病毒剂，通过N-杂环卡宾催化腈形成反应的关键步骤合成了一类具有优异光学纯度的平面手性硫脲分子，用于对植物病毒PVY的抗病毒评价。