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Human Infrapatellar Fat Pad Mesenchymal Stem Cell-derived Extracellular Vesicles Purified by Anion Exchange Chromatography Suppress Osteoarthritis Progression in a Mouse Model.
Clinical Orthopaedics and Related Research ( IF 4.2 ) Pub Date : 2024-04-19 , DOI: 10.1097/corr.0000000000003067
Qisong Liu 1 , Jianqun Wu 2 , Hua Wang 1 , Zhaofeng Jia 1 , Guangheng Li 1, 2
Affiliation  

Extracellular vesicles derived from mesenchymal stem cells (MSCs) show great promise in treating osteoarthritis (OA). However, studies from the perspective of clinical feasibility that consider an accessible cell source and a scalable preparation method for MSC-extracellular vesicles are lacking.

中文翻译:

通过阴离子交换色谱法纯化的人髌下脂肪垫间充质干细胞来源的细胞外囊泡可抑制小鼠模型中的骨关节炎进展。

源自间充质干细胞(MSC)的细胞外囊泡在治疗骨关节炎(OA)方面显示出巨大的前景。然而,缺乏从临床可行性角度考虑MSC细胞外囊泡的可获取细胞来源和可扩展制备方法的研究。
更新日期:2024-04-19
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