Cockroaches are widely acknowledged as significant vectors of pathogenic microorganisms. The Periplaneta fuliginosa densovirus (PfDNV) infects the smoky-brown cockroach P. fuliginosa and causes host mortality, which identifies the PfDNV as a species-specific and environmentally friendly biopesticide. However, although the biochemical characterization of PfDNV has been extensively studied, the immune response against PfDNV remains largely unclear.

中文翻译：

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Ben-JNK 信号传导是黑大蠊浓核病毒感染期间宿主死亡所必需的

蟑螂被广泛认为是病原微生物的重要载体。黑大蠊浓核病毒(PfDNV) 感染烟褐色蟑螂P. fuliginosa并导致宿主死亡，这表明 PfDNV 是一种物种特异性且环境友好的生物农药。然而，尽管 PfDNV 的生化特征已被广泛研究，但针对 PfDNV 的免疫反应仍不清楚。