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Data-driven decomposition and staging of flortaucipir uptake in Alzheimer's disease
Alzheimer's & Dementia ( IF 14.0 ) Pub Date : 2024-04-29 , DOI: 10.1002/alz.13769
Tom Earnest 1 , Abdalla Bani 1 , Sung Min Ha 1 , Diana A. Hobbs 1 , Deydeep Kothapalli 1 , Braden Yang 1 , John J. Lee 1 , Tammie L. S. Benzinger 1 , Brian A. Gordon 1 , Aristeidis Sotiras 1, 2 ,
Affiliation  

Previous approaches pursuing in vivo staging of tau pathology in Alzheimer's disease (AD) have typically relied on neuropathologically defined criteria. In using predefined systems, these studies may miss spatial deposition patterns which are informative of disease progression.

中文翻译:

阿尔茨海默病中弗洛托西吡摄取的数据驱动分解和分期

先前对阿尔茨海默病 (AD) 中 tau 病理学进行体内分期的方法通常依赖于神经病理学定义的标准。在使用预定义系统时,这些研究可能会错过可提供疾病进展信息的空间沉积模式。
更新日期:2024-04-30
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