Human neuroimaging studies of episodic memory retrieval routinely observe the engagement of specific cortical regions beyond the medial temporal lobe. Of these, medial parietal cortex (MPC) is of particular interest given its distinct functional characteristics during different retrieval tasks. Specifically, while recognition and autobiographical recall tasks are both used to probe episodic retrieval, these paradigms consistently drive distinct spatial patterns of response within MPC. However, other studies have emphasized alternate MPC functional dissociations in terms of brain network connectivity profiles or stimulus category selectivity. As the unique contributions of MPC to episodic memory remain unclear, adjudicating between these different accounts can provide better consensus regarding MPC function. Therefore, we used a precision-neuroimaging dataset (7T functional magnetic resonance imaging) to examine how MPC regions are differentially engaged during recognition memory and how these task-related dissociations may also reflect distinct connectivity and stimulus category functional profiles. We observed interleaved, though spatially distinct, subregions of MPC where responses were sensitive to either recognition decisions or the semantic representation of stimuli. In addition, this dissociation was further accentuated by functional subregions displaying distinct profiles of connectivity with the hippocampus during task and rest. Finally, we show that recent observations of dissociable person and place selectivity within the MPC reflect category-specific responses from within identified semantic regions that are sensitive to mnemonic demands. Together, by examining precision functional mapping within individuals, these data suggest that previously distinct observations of functional dissociation within MPC conform to a common principle of organization throughout hippocampal–neocortical memory systems.

情景记忆检索的人类神经影像学研究通常会观察内侧颞叶以外的特定皮质区域的参与情况。其中，内侧顶叶皮层（MPC）因其在不同检索任务中独特的功能特征而特别令人感兴趣。具体来说，虽然识别和自传回忆任务都用于探索情景检索，但这些范式始终驱动 MPC 内不同的空间响应模式。然而，其他研究强调了大脑网络连接概况或刺激类别选择性方面的替代 MPC 功能分离。由于 MPC 对情景记忆的独特贡献仍不清楚，在这些不同的帐户之间进行裁决可以就 MPC 功能提供更好的共识。因此，我们使用精密神经成像数据集（7T 功能磁共振成像）来检查 MPC 区域在识别记忆过程中如何有差异地参与，以及这些与任务相关的解离如何也反映了不同的连接性和刺激类别功能概况。我们观察到 MPC 的交错但在空间上不同的子区域，其中响应对识别决策或刺激的语义表示敏感。此外，在任务和休息期间，功能分区与海马体表现出不同的连接特征，进一步加剧了这种分离。最后，我们表明，最近对 MPC 内的分离者和位置选择性的观察反映了对助记符要求敏感的已识别语义区域内的特定类别响应。总之，通过检查个体内部的精确功能映射，这些数据表明，先前对 MPC 内功能分离的独特观察符合整个海马-新皮质记忆系统的共同组织原则。