A piezoelectric micropump (PE pump) was proposed featuring a multi-plate cantilever valve (MPCV) and a ramp channel (RC) to deliver high performance in a compact design. Both the MPCV and RC underwent thorough theoretical, simulation-based, and experimental evaluations. A specialized driver plate was then developed to precisely control the PE pump. Key parameters of the PE pump were optimized based on test results. The final phase involved assessing the PE pump's output performance through tests, including a simulated insulin infusion scenario. The findings revealed that the MPCV exhibited a pronounced rectification capability, significantly enhancing the pump's operational efficiency over traditional designs. The RC, on the other hand, effectively minimized fluid resistance, capitalizing on the fluid inertia effect for improved performance. Integrating the MPCV and RC aligned the fluid path from inlet to outlet closely parallel to the PE vibrator. This alignment reduced backflow, thereby improving the micropump's output efficiency. Operating at 240 voltage peak-to-peak (Vpp) and 230 Hz, the PE pump demonstrated a flow rate of 6.8 ml/min and an output pressure of 68.6 kPa while maintaining a compact size of merely 10 × 10 × 1.5 mm. The precision in flow rate adjustment was refined to 0.15 μl, with the deviation in insulin delivery being approximately ± 3 %. The study presents a prototype for a continuous subcutaneous insulin infusion protocol, leveraging the PE pump's advanced features.

中文翻译：

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专为精确输送而设计的高性能压电微型泵

提出了一种压电微型泵（PE 泵），具有多板悬臂阀（MPCV）和斜坡通道（RC），可在紧凑的设计中提供高性能。 MPCV 和 RC 都经过了彻底的理论、基于仿真和实验的评估。随后开发了专用驱动板来精确控制 PE 泵。根据试验结果对PE泵的关键参数进行了优化。最后阶段涉及通过测试评估 PE 泵的输出性能，包括模拟胰岛素输注场景。研究结果表明，MPCV 表现出显着的整流能力，与传统设计相比，显着提高了泵的运行效率。另一方面，RC 有效地最小化了流体阻力，利用流体惯性效应来提高性能。 MPCV 和 RC 的集成使从入口到出口的流体路径与 PE 振动器紧密平行。这种排列减少了回流，从而提高了微型泵的输出效率。 PE 泵在 240 电压峰峰值 (Vpp) 和 230 Hz 下运行，流量为 6.8 ml/min，输出压力为 68.6 kPa，同时保持仅为 10 × 10 × 1.5 mm 的紧凑尺寸。流量调节精度精确至0.15μl，胰岛素输送偏差约为±3%。该研究利用 PE 泵的先进功能，提出了连续皮下胰岛素输注方案的原型。