AimTo evaluate the effectiveness of a flapless surgical approach in the treatment of peri‐implantitis and to explore the factors influencing its outcome.Materials and MethodsThe present retrospective study evaluated patients with at least one implant diagnosed with peri‐implantitis and treated with a flapless surgical access, with or without systemic antimicrobials, curettage and, when needed, prostheses modification. Clinical and radiographic parameters were assessed at baseline and at 3 months and at least 12 months. The primary outcome was disease resolution (≤1 bleeding sites, probing depth [PD] ≤5 mm, no bone loss >0.5 mm). Multilevel regression analyses were used to identify predictors influencing the probability of attaining disease resolution.ResultsOne hundred and seventeen patients with 338 implants were included. Disease resolution was attained in 54.4% of the 338 implants receiving flapless surgical access. At the end of the follow‐up period, 111 patients (94.9%) with 295 implants (87.3%) did not require any further treatment, with 81.4% of these implants presenting PD ≤ 5 mm. History of periodontitis and PD at baseline were identified as negative predictors, while compliance with supportive peri‐implant care, a machined surface and the adjunctive use of systemic azithromycin or metronidazole were identified as positive predictive factors for disease resolution.ConclusionsA flapless surgical approach led to disease resolution in 54.4% of the implants with peri‐implantitis. Several risk/protective predictors for disease resolution were identified.

中文翻译：

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无翻瓣手术结合种植体表面净化和辅助全身抗生素治疗种植体周围炎：回顾性病例系列研究

目的 评估无翻瓣手术方法治疗种植体周围炎的有效性，并探讨影响其结果的因素。材料和方法本回顾性研究评估了至少一颗种植体被诊断为种植体周围炎并接受无翻瓣手术治疗的患者，使用或不使用全身抗菌药物、刮除术，以及在需要时进行假体改造。在基线、3 个月和至少 12 个月时评估临床和放射学参数。主要结局是疾病消退（≤1 个出血部位，探诊深度 [PD] ≤5 mm，无骨质流失 >0.5 mm）。使用多级回归分析来确定影响疾病解决概率的预测因素。结果纳入了 117 名患者，植入了 338 个种植体。在接受无翻瓣手术的 338 个种植体中，54.4% 的疾病得到缓解。随访期结束时，拥有 295 个种植体 (87.3%) 的 111 名患者 (94.9%) 不需要任何进一步治疗，其中 81.4% 的种植体出现 PD ≤ 5 mm。基线时的牙周炎和 PD 病史被确定为阴性预测因素，而对种植体周围支持性护理的依从性、机械加工表面以及全身阿奇霉素或甲硝唑的辅助使用被确定为疾病缓解的阳性预测因素。结论54.4% 患有种植体周围炎的种植体的疾病得到缓解。确定了疾病解决的几个风险/保护性预测因素。