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Aptamer-modified paper-based analytical devices for the detection of food hazards: Emerging applications and future perspective
Biotechnology Advances ( IF 16.0 ) Pub Date : 2024-04-30 , DOI: 10.1016/j.biotechadv.2024.108368
Mingwei Qin , Imran Mahmood Khan , Ning Ding , Shuo Qi , Xiaoze Dong , Yin Zhang , Zhouping Wang

Food analysis plays a critical role in assessing human health risks and monitoring food quality and safety. Currently, there is a pressing need for a reliable, portable, and quick recognition element for point-of-care testing (POCT) to better serve the demands of on-site food analysis. Aptamer-modified paper-based analytical devices (Apt-PADs) have excellent characteristics of high portability, high sensitivity, high specificity, and on-site detection, which have been widely used and concerned in the field of food safety. The article reviews the basic components and working principles of Apt-PADs, and introduces their representative applications detecting food hazards. Finally, the advantages, challenges, and future directions of Apt-PADs-based sensing performance are discussed, to provide new directions and insights for researchers to select appropriate Apt-PADs according to specific applications.

中文翻译:

用于检测食品危害的适体修饰纸基分析装置:新兴应用和未来前景

食品分析在评估人类健康风险和监测食品质量和安全方面发挥着至关重要的作用。目前,迫切需要一种可靠、便携、快速的即时检测(POCT)识别元件,以更好地满足现场食品分析的需求。核酸适体修饰纸基分析装置(Apt-PADs)具有高便携性、高灵敏度、高特异性、可现场检测等优良特性,在食品安全领域得到了广泛的应用和关注。文章回顾了Apt-PAD的基本组成和工作原理,并介绍了其在食品危害检测方面的代表性应用。最后,讨论了基于 Apt-PAD 的传感性能的优势、挑战和未来方向,为研究人员根据具体应用选择合适的 Apt-PAD 提供新的方向和见解。
更新日期:2024-04-30
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