Yogurt Prevents Colorectal Tumorigenesis in ApcMin/+ Mice,Molecular Nutrition & Food Research

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Yogurt Prevents Colorectal Tumorigenesis in ApcMin/+ Mice
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2024-05-03 , DOI: 10.1002/mnfr.202300737
Xiaojing Li _{1,

2} , Jin Qian _{1,

2} , Qinglong Liu _{1,

2} , Min Guo _{1,

2} , Hao Zhang _{1,

2} , Haitao Li _{1,

2} , Wei Chen _{1,

2}

Affiliation

Yogurt consumption is related to a decreased risk of colorectal cancer (CRC), but whether such association is causal remains unclear. Patients with familial adenomatous polyposis (FAP) are at increased risk of CRC development. Here, the study investigates the efficacy of yogurt for intestinal polyposis chemoprevention in Apc^Min/+ mice, a preclinical model for human FAP.

中文翻译：

酸奶可预防 ApcMin/+ 小鼠结直肠肿瘤的发生

饮用酸奶与结直肠癌 (CRC) 风险降低有关，但这种关联是否存在因果关系仍不清楚。家族性腺瘤性息肉病 (FAP) 患者发生 CRC 的风险增加。在此，该研究调查了酸奶对 Apc ^Min/+ 小鼠肠息肉病化学预防的功效，Apc ^Min/+ 小鼠是人类 FAP 的临床前模型。

更新日期：2024-05-03

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