Designing photoelectrochemical sensors for detecting ultra-trace amounts of Aflatoxin B1 (AFB1) in complex samples poses a significant challenge. In pursuit of this objective, we engineered hollow-structured ZnCdS (denoted as h-ZnCdS) material and applied an electrodeposition method to introduce Au nanoparticles (AuNPs) on the surface. This approach resulted in a significant enhancement of the photocurrent response of the photoelectrode, attributed to the synergistic effects of the hollow structure and surface plasmon resonance, thereby underscoring its potential for advanced applications. Utilizing density functional theory, we computed the transfer route and energy band formation of photogenerated electrons. Subsequently, we developed an AFB1 photoelectrochemical (PEC) aptasensor based on the competition mechanism, coupled with aptamer probe technology. This aptasensor allows for the ultra-trace determination of AFB1, exhibiting a remarkable detection limit as low as 1.32 fg/mL and a linear range from 1.0 × 10 to 100.0 pg/mL. The PEC aptasensor for AFB1 demonstrates excellent sensitivity and selectivity. When applied to the detection of AFB1 in Tsaoko, wheat, and corn samples, its performance aligns closely with high-performance liquid chromatography (HPLC) results, validating its applicability for analyzing real-world samples.

中文翻译：

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通过基于 h-Zn1Cd5S 的光电化学适体传感器提高食品中黄曲霉毒素 B1 检测的灵敏度

设计用于检测复杂样品中超痕量黄曲霉毒素 B1 (AFB1) 的光电化学传感器是一项重大挑战。为了实现这一目标，我们设计了中空结构的 ZnCdS（表示为 h-ZnCdS）材料，并应用电沉积方法在表面引入金纳米颗粒（AuNP）。由于中空结构和表面等离子体共振的协同效应，这种方法导致光电极的光电流响应显着增强，从而强调了其先进应用的潜力。利用密度泛函理论，我们计算了光生电子的传输路径和能带形成。随后，我们开发了基于竞争机制并结合适配体探针技术的AFB1光电化学（PEC）适配体传感器。该适体传感器可实现 AFB1 的超痕量测定，检测限低至 1.32 fg/mL，线性范围为 1.0 × 10 至 100.0 pg/mL。 AFB1 的 PEC 适体传感器表现出出色的灵敏度和选择性。当应用于草果、小麦和玉米样品中 AFB1 的检测时，其性能与高效液相色谱 (HPLC) 结果密切相关，验证了其分析实际样品的适用性。