Leaderless foot-and-mouth disease virus serotype O did not cause clinical disease and failed to establish a persistent infection in cattle,Emerging Microbes & Infections

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Leaderless foot-and-mouth disease virus serotype O did not cause clinical disease and failed to establish a persistent infection in cattle
Emerging Microbes & Infections ( IF 13.2 ) Pub Date : 2024-05-16 , DOI: 10.1080/22221751.2024.2348526
Benedikt Litz ₁ , Julia Sehl-Ewert ₂ , Angele Breithaupt ₂ , Anja Landmesser ₁ , Florian Pfaff ₁ , Aurore Romey ₃ , Sandra Blaise-Boisseau ₃ , Martin Beer ₁ , Michael Eschbaumer ₁

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The foot-and-mouth disease virus (FMDV) Leader proteinase Lpro inhibits host mRNA translation and blocks the interferon response which promotes viral survival. Lpro is not required for viral replic...

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