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Perplexing case of abdominal pain with eosinophilia and fasciitis
Gut ( IF 24.5 ) Pub Date : 2024-05-06 , DOI: 10.1136/gutjnl-2024-332580
Robert Sean O'Neill , Logan Gardner , Anthony Kelleher , Roger Pamphlett , Laila Girgis , Alina Stoita

A 34-year-old man presented to our institution for review with recurrent abdominal pain, constipation, lethargy, fevers and episodic migratory soft tissue severe cellulitis of the limbs after minimal exercise. This was on a background of a diagnosis of eosinophilic enterocolitis at the age of 10 when due to recurrent abdominal pain, endoscopy was performed with biopsies showing eosinophilic infiltration of the oesophagus, stomach, duodenum and colon. This had been treated with steroids in the past with clinical response. A variety of disease-modifying antirheumatic drugs (DMARDs) failed to provide a steroid-sparing effect previously. Clinical history was otherwise significant for resolved childhood asthma and eczema. The patient underwent a gastroscopy and colonoscopy which demonstrated oesophageal (figure 1A), stomach, duodenal and terminal ileal eosinophilic infiltration, along with pancolitis on colonic …

中文翻译:

腹痛伴嗜酸性粒细胞增多和筋膜炎的复杂病例

一名 34 岁男性因少量运动后反复出现腹痛、便秘、嗜睡、发烧和四肢阵发性迁移性软组织严重蜂窝织炎而到我们机构就诊。这是在10岁时诊断出嗜酸性小肠结肠炎的背景下,由于反复腹痛,进行内窥镜检查,活检显示食管、胃、十二指肠和结肠有嗜酸性粒细胞浸润。过去曾用类固醇治疗过此病并取得临床反应。此前,多种缓解疾病的抗风湿药物 (DMARD) 未能提供类固醇节约作用。临床病史对于解决儿童哮喘和湿疹也很重要。该患者接受了胃镜检查和结肠镜检查,结果显示食管(图 1A)、胃、十二指肠和回肠末端嗜酸性粒细胞浸润,以及结肠全结肠炎……
更新日期:2024-05-07
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