In this issue of Developmental Cell, Fowler et al. applied genetic lineage-tracing mouse models to support the notion that artery endothelial cells are the predominant source of hematopoietic stem cells. They leveraged this and developed a method capable of efficiently differentiating human pluripotent stem cells into HLF⁺HOXA⁺ hematopoietic progenitors.

中文翻译：

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追踪胚胎造血过程指导多能干细胞诱导成造血祖细胞

在本期《发育细胞》中，福勒等人。应用遗传谱系追踪小鼠模型来支持动脉内皮细胞是造血干细胞的主要来源的观点。他们利用这一点，开发了一种能够有效地将人类多能干细胞分化为HLF ⁺ HOXA ⁺造血祖细胞的方法。