Anthropogenic pollution poses a threat to marine conservation by causing chronic toxic effects. Seabirds have contact throughout their lives with pollutants like plastic, metals, polychlorinated biphenyls (PCBs), and organochlorine pesticides such as hexachlorocyclohexanes (HCHs). We assessed 155 Manx shearwaters () stranded along the Brazilian coast, analyzing associations between organic pollutants, plastic ingestion, biomarkers (transcript levels of , [], [], [], and genes) and enzymes activity (ethoxy-resorufin O-deethylase and glutathione -transferase [GST]). Plastic debris was found in 29 % of the birds. The transcription of and was significantly associated with hexachlorobenzene (HCB) and PCBs levels. was associated with HCB and Mirex, and GST was associated with Drins and Mirex. While organic pollutants affected shearwaters more than plastic ingestion, reducing plastic availability remains relevant as xenobiotics are also potentially adsorbed onto plastics.

中文翻译：

---

越冬马恩岛海鸥（Puffinus puffinus）的生化和分子生物标志物及其与人为化学物质的关联

人为污染会造成慢性毒性效应，对海洋保护构成威胁。海鸟一生都会接触塑料、金属、多氯联苯 (PCB) 和六氯环己烷 (HCH) 等有机氯农药等污染物。我们评估了 155 只滞留在巴西海岸的马恩岛海鸥 ()，分析了有机污染物、塑料摄入、生物标志物（、[]、[]、[] 和基因的转录水平）和酶活性（乙氧基试卤灵 O-脱乙基酶）之间的关联。和谷胱甘肽转移酶 [GST]）。 29% 的鸟类体内发现了塑料碎片。和 的转录与六氯苯 (HCB) 和 PCB 水平显着相关。与 HCB 和 Mirex 相关，GST 与 Drins 和 Mirex 相关。虽然有机污染物对海鸥的影响大于塑料摄入，但减少塑料的可用性仍然具有重要意义，因为异生素也可能被吸附到塑料上。