In this paper, a green, cost-effective sample preparation method based on air assisted liquid phase microextraction (AA-LPME) was developed for the simultaneous extraction of As(III) and Sb(III) ions from vegetable samples using hydrophilic/hydrophobic natural deep eutectic solvents (NADESs). Central composite design was used for the optimization of extraction factors including NADES volume, extraction cycle, pH, and curcumin concentration. Limits of detection for As(III) and Sb(III) were 1.5 ng L and 0.06 ng L, respectively. Working ranges for As(III) and Sb(III) were 0.2–300 ng L (coefficient of determination (R = 0.9978) and 5–400 ng L (R = 0.9996), respectively. Relative standard deviations for As(III) and Sb(III) were 2.2–2.8% and 2.9–3.2%, respectively. Enrichment factor of the method was 184 for As(III) and 172 for Sb(III). The accuracy and precision of the AA-NADES-LPME method were investigated by intraday/interday studies and standard reference material analysis, respectively. Finally, the AA-NADES-LPME method was successfully applied to microwave digested vegetable samples using the standard addition approach and acceptable recoveries were achieved.

中文翻译：

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使用亲水/疏水 NADES 选择性萃取蔬菜样品中 As(III) 和 Sb(III) 离子的研究：空气辅助液相微萃取和化学计量学优化


本文开发了一种基于空气辅助液相微萃取 (AA-LPME) 的绿色、经济高效的样品制备方法，用于使用亲水/疏水天然物质同时萃取蔬菜样品中的 As(III) 和 Sb(III) 离子。低共熔溶剂 (NADES)。使用中心复合设计来优化提取因素，包括 NADES 体积、提取周期、pH 值和姜黄素浓度。 As(III) 和 Sb(III) 的检测限分别为 1.5 ng·L 和 0.06 ng·L。 As(III) 和 Sb(III) 的工作范围分别为 0.2–300 ng L（测定系数 (R = 0.9978) 和 5–400 ng L (R = 0.9996)。As(III) 和 Sb(III) 的相对标准偏差Sb(III) 分别为 2.2–2.8% 和 2.9–3.2%，As(III) 的富集因子为 184，Sb(III) 的富集因子为 172。 AA-NADES-LPME 方法的准确度和精密度为。分别通过日内/日间研究和标准参考物质分析进行研究，最后，使用标准添加方法将 AA-NADES-LPME 方法成功应用于微波消解的蔬菜样品，并取得了可接受的回收率。